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Professor Andrey Karlyshev

Professor of Microbiology, Kingston University.

Professor Andrey Karlyshev Areas of expertise

Find out more about Professor Andrey Karlyshev

Overview

Andrey Karlyshev is a professor of microbiology at Kingston University with research interests in applied, environmental and medical microbiology. He has a particular interest in Campylobacter jejuni, which is now recognised as one of the main bacterial causes of gastro-intestinal diseases world-wide. Indeed in the UK alone this accounts for more than 50,000 cases per year.

Professor Karlyshev has had more than 70 papers published in esteemed journals, and been an invited speaker at conferences around the world. He has been on the editorial board of the journals Advances in Life Sciences and Asian Pacific Journal of Tropical Medicine, and has been a reviewer for articles submitted to leading journals in his field.

Qualifications

Year gained Subject
1981 PhD in Molecular Biology, Institute of Molecular, Moscow, Russia.
1976 BSc(Hons), Chemistry and Molecular Biology, Moscow State University.

Career Highlights

Year Position held
2008 - Professor of Microbiology, School of Life Sciences, Kingston University.
2004 - 2008 Senior lecturer, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London.
2002 - 2004 Lecturer, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London.
1999 - 2002 Research fellow, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London.
1996 - 1999 Research fellow, St Batholomew's and Royal London School of Medicine and Dentistry, QMW College, London.
1993 - 1996 Postdoctoral research fellow, University of Reading, UK.
1991 - 1992 Principal scientist, Institute of Immunology, Moscow region, London.
1987 - 1991 Senior researcher, Institute of Applied Microbiology, Moscow region, Russia.
1981 - 1987 Junior researcher, Institute of Applied Microbiology, Moscow region, Russia.

Research

Papers:

Karlyshev A.V., Kudryashova E.B. and Ariskina E.V. (2016) Draft Genome Sequence of "Cohnella kolymensis" B-2846
Genome Announc. 2016 Jan 14;4(1). pii: e01587-15. doi: 10.1128/genomeA.01587-15. PMID:26769947

Karlyshev A.V., Khlebnikov V.C., Kosarev I.V. and Abramov VM. (2016) Draft Genome Sequence of Lactobacillus plantarum 2025.
Genome Announc. 2016 Jan 7;4(1). pii: e01532-15. doi: 10.1128/genomeA.01532-15. PMID:26744375

Karlyshev A.V., Villena J., Gonzalez C., Albarracin L., Barros J. and Garcia A. (2015)
Draft Genome Sequence of a Probiotic Strain, Lactobacillus fermentum UCO-979C.
Genome Announc. 2015 Dec 10;3(6). pii: e01439-15. doi: 10.1128/genomeA.01439-15.PMID:26659681

Lehri B, Seddon A. M. and Karlyshev A. V. (2015) Plasmid and chromosome-encoded adhesion-related genes of Lactobacillus fermentum revealed by genome sequencing. FEMS Microbiol Lett. PMID:25908870

Karlyshev A.V., Snyder L.A, McFadden J. and Griffin R. (2015) Insight into proteomic investigations of Neisseria meningitidis serogroup C strain L91543 from analysis of its genome sequence. FEMS Microbiol Lett. PMID:25846515

Vieira A., Seddon A. M and Karlyshev A. V. (2015) Campylobacter-Acanthamoeba interactions. Microbiology. doi: 10.1099/mic.0.000075. PMID:25757600

Lehri B., Kukreja K., Vieira A., Zaremba M., Bonney K. and Karlyshev A.V. (2015) Specific genetic features of Campylobacter jejuni strain G1 revealed by genome sequencing. FEMS Microbiology Letters doi: 10.1093/femsle/fnu064

Karlyshev A. V., Thacker G., Jones M.A., Clements M.O. and Wren B.W.  (2014) Campylobacter jejuni gene cj0511 encodes a serine peptidase essential for colonisation. FEBS Open Bio 4:468-72. doi: 10.1016/j.fob.2014.04.012. eCollection 2014.PMID: 24918062

Rubinchik S., Seddon A.M. and Karlyshev A.V. (2014) A negative effect of Campylobacter capsule on bacterial interaction with an analogue of a host cell receptor. BMC Microbiology

Karlyshev A. V., Robyn J., Rasschaert G. and Heyndrickx M. (2014) Draft Genome Sequence of Enterococcus faecalis MB5259. Genome Announcements 2(3). pii: e00634-14. doi: 10.1128/genomeA.00634-14. PMID:24948775

Abramov V., Khlebnikov V., Kosarev I., Bairamova G., Vasilenko R., Suzina N., Machulin A., Sakulin V., Kulikova N., Vasilenko N., Karlyshev A., Uversky V., Chikindas M.L., Melnikov V. Probiotic Properties of Lactobacillus crispatus 2,029: Homeostatic Interaction with Cervicovaginal Epithelial Cells and Antagonistic Activity to Genitourinary Pathogens. Probiotics Antimicrob Proteins. 2014 Jul 16. [Epub ahead of print] PMID:25028263

Karlyshev A. V., Melnikov V. G. And Chistyakov V.A. (2014). Draft Genome Sequence of Bacillus amyloliquefaciens B-1895. Genome Announcements 2(3). pii: e00633-14. doi: 10.1128/genomeA.00633-14. PMID:24948774

Karlyshev A. V., Melnikov V. G. and Michael L. Chikindas M.L.  (2014). Draft Genome Sequence of Bacillus subtilis strain KATMIRA1933. Genome Announcements (in press) 2(3). pii: e00619-14. doi: 10.1128/genomeA.00619-14. PMID:24948771

Karlyshev A. V., Melnikov V. G., Kosarev I. V. and Abramov V. M. (2014) Draft Genome Sequence of Lactobacillus rhamnosus 2166. Genome Announc. 2(1). pii: e01222-13. doi: 10.1128/genomeA.01222-13. Free PMC Article

Karlyshev A. V., Melnikov V. G. , Khlebnikov V. C., Abramov V. M. (2014) Draft Genome Sequence of Lactobacillus crispatus 2029. Genome Announc. 2(1). pii: e01221-13. doi: 10.1128/genomeA.01221-13. Free PMC Article

Karlyshev A. V. and Abramov V. M. (2014) Draft Genome Sequence of Lactobacillus plantarum 2165. Genome Announc. 9;2(1). pii: e01179-13. doi: 10.1128/genomeA.01179-13. Free PMC Article

Van Alphen L., Wenzel C.Q., Richards M.R., Fodor C., Ashmus R.A., Stahl M., Karlyshev A.V., Wren B.W., Stinzi, A., Miller, W.G., Lawary T.L. and Szymanski, C.M. (2014) Biological roles of the O-methyl phosphoramidate capsule modification in Campylobacter jejuni. PLoS One.  PMID: 24498018. doi: 10.1371

Karlyshev A. V., Raju K. and Abramov V. M. (2013) Draft Genome Sequence of Lactobacillus fermentum strain 38172. Genome announcements 1 (6) doi:pii: e01006-13. 10.1128/genomeA.01006-13

Karlyshev A. V., Nadaradjah S. and and Abramov V. M. (2013) Draft Genome Sequence of Lactobacillus jensenii strain MD IIE-70(2). Genome announcements 1 (6) doi:pii: e01005-13. 10.1128/genomeA.01005-13

Karlyshev, A. V., Quail, M. A., Parkhill, J. and Wren, B. W. (2013) Unusual features in organisation of capsular polysaccharide-related genes of C-jejuni strain X. Gene, 522(1), pp. 37-45. ISSN (print) 0378-1119

Karlyshev, A.V., Melnikov, V.G., Kosarev, I.V., Khlebnikov, V.C., Sukhikh, G.T. and Abramov, V.M.(2013) Draft Genome Sequence of Lactobacillus gasseri Strain 2016. Genome Announcements, 22(1), ISSN (print) 2169-8287

Karlyshev, Andrey V. and Melnikov, Vyacheslav G. (2013) Draft genome sequence of Corynebacterium pseudodiphtheriticum Strain 090104 "Sokolov". Genome announcements, 1(6), ISSN (print) 2169-8287

Rubinchik, S., Seddon, A. and Karlyshev, Andrey V. (2012) Molecular mechanisms and biological role of Campylobacter jejuni attachment to host cells. European Journal of Microbiology and Immunology, 2(1), pp. 32-40. ISSN (print) 2062-509X

Ikeda, N. and Karlyshev, Andrey V. (2012) Putative mechanisms and biological role of coccoid form formation in Campylobacter jejuni. European Journal of Microbiology and Immunology, 2(1), pp. 41-49. ISSN (print) 2062-509X

Champion, Olivia L., Karlyshev, Andrey, Cooper, A. M., Ford, Donna C., Wren, Brendan W., Duffield, Melanie, Oyston, Petra C. F. and Titball, Richard W. (2011) 'Yersinia pseudotuberculosis' mntH functions in intracellular manganese accumulation, which is essential for virulence and survival in cells expressing functional Nramp1. Microbiology, 157(4), pp. 1115-1122. ISSN (print) 1350-0872

Champion, Olivia L, Karlyshev, Andrey V, Senior, Nicola J, Woodward, Martin, La Ragione, Roberto,Howard, Sarah L, Wren, Brendan W and Titball, Richard W (2010) Insect infection model for Campylobacter jejuni reveals that O-methyl phosphoramidate has insecticidal activity. The Journal of Infectious Diseases, 201(5), pp. 776-782. ISSN (print) 0022-1899

Stubben, Chris J , Duffield, Melanie L, Cooper, Ian A, Ford, Donna C, Gans, Jason D, Karlyshev, Andrey, Lingard, Brian, Oyston, Petra C F, de Rochefort, Anna, Song, Jian, Wren, Brendan W ,Titball, Rick W and Wolinsky, Murray (2009) Steps toward broad-spectrum therapeutics: discovering virulence-associated genes present in diverse human pathogens. BMC Genomics, 10(501), pp. 1-9. ISSN (online) 1471-2164

Champion, Olivia L, Coope, Ian A M, James, Sarah L, Ford, Donna, Karlyshev, Andrey, Wren, Brendan W, Duffield, Melanie , Oyston, Petra C F and Titball, Richard W (2009) Galleria mellonella as an alternative infection model for Yersinia pseudotuberculosis. Microbiology, 155(5), 1516 -1522.

Corcionivoschi, N, Clyne, M, Lyons, A, Elmi, A, Gundogdu, O, Wren, B W, Dorrell, N, Karlyshev, Andrey and Bourke, B (2009) Campylobacter jejuni cocultured with epithelial cells reduces surface capsular polysaccharide expression. Infection and Immunity, 77(5), pp. 1959-1967. ISSN (print) 0019-9567

Howard, SL, Jagannathan, A, Soo, EC, Hui, JPM, Aubry, AJ, Ahmed, I, Karlyshev, Andrey, Kelly, JF,Jones, MA, Stevens, MP, Logan, SM and Wren, BW (2009) Campylobacter jejuni Glycosylation Island important in cell charge, legionaminic acid biosynthesis, and colonization of chickens. Infection and Immunity, 77(6), pp. 2544-2556. ISSN (print) 0019-9567

McNally, D. J., Lamoureux, M. P., Karlyshev, A. V., Fiori, L. M., Li, J., Thacker, G., Coleman, R. A.,Khieu, N. H., Wren, B. W., Brisson, J., Jarrell, H. C. and Szymanski, C. M. (2007) Commonality and Biosynthesis of the O-Methyl Phosphoramidate Capsule Modification in Campylobacter jejuni. Journal of Biological Chemistry, 282(39), pp. 28566-28576. ISSN (print) 0021-9258

Joshua, G. W. P., Guthrie-Irons, C. and Karlyshev, A. V. (2006) Biofilm formation in Campylobacter jejuni. Microbiology, 152(2), pp. 387-396. ISSN (print) 1350-0872

Karlyshev, A. V. and Wren, B. W. (2005) Development and application of an insertional system for gene delivery and expression in Campylobacter jejuni. Applied and Environmental Microbiology, 71(7), pp. 4004-4013. ISSN (print) 0099-2240

Karlyshev, Andrey V., Ketley, Julian M. and Wren, Brendan W. (2005) The Campylobacter jejuni glycome. FEMS microbiology reviews, 29(2), pp. 377-390. ISSN (print) 0168-6445

Linton, Dennis, Dorrell, Nick, Hitchen, Paul G., Amber, Saba, Karlyshev, Andrey V., Morris, Howard R., Dell, Anna, Valvano, Miguel A., Aebi, Markus and Wren, Brenden W. (2005) Functional analysis of the Campylobacter jejuni N-linked protein glycosylation pathway. Molecular Microbiology, 55(6), 1695-1703 . ISSN (print) 0950-382X

Hitchen, P G , Dorrel , N, Amber, S, Karlyshev, Andrey, Morris , H R, Dell, A, Valvano , M A, Aebi , Mand Wren , B W (2004) Functional analysis of a novel bacterial N-linked protein glycosylation pathway from Campylobacter jejuni. Glycobiology, 14(11), pp. 1124-1125.

Karlyshev, Andrey V., Champion, Olivia G., Churcher, Carol, Brisson, Jean-Robert, Jarrell, Harold G.,Gilbert, Michael, Brochu, Denis, St Michael, Frank, Li, Jianjun, Wakarchuk, Warren W., Goodhead, Ian, Sanders, Mandy, Stevens, Kim, White, Brian, Parkhill, Julian, Wren, Brendan W. and Szymanski, Christine M. (2004) Analysis of Campylobacter jejuni capsular loci reveals multiple mechanisms for the generation of structural diversity and the ability to form complex heptoses. Molecular Microbiology, 55(1), pp. 90-103. ISSN (print) 0950-382X

Jones, M. A., Marston, K. L., Woodall, C. A., Maskell, D. J., Linton, D, Karlyshev, A. V., Dorrell, N,Wren, B. W. and Barrow, P. A. (2004) Adaptation of Campylobacter jejuni NCTC11168 to High-Level Colonization of the Avian Gastrointestinal Tract. Infection and Immunity, 72(7), pp. 3769-3776. ISSN (print) 0019-9567

Karlyshev, A. V., Everest, P, Linton, D, Cawthraw, S, Newell, D. G. and Wren, B. W. (2004) The Campylobacter jejuni general glycosylation system is important for attachment to human epithelial cells and in the colonization of chicks. Microbiology, 150(6), pp. 1957-1964. ISSN (print) 1350-0872

Joshua, G. W. P., Karlyshev, A. V., Smith, M. P., Isherwood, K. E., Titball, R. W. and Wren, B. W.(2003) A Caenorhabditis elegans model of Yersinia infection: biofilm formation on a biotic surface.Microbiology, 149(11), pp. 3221-3229. ISSN (print) 1350-0872

Linton, D, Allan, E, Karlyshev, A.V., Cronshaw, A.D. and Wren, B.W. (2002) Identification of N-acetylgalactosamine-containing glycoproteins PEB3 and CgpA in Campylobacter jejuni. Molecular Microbiology, 43(2), pp. 497-508. ISSN (print) 0950-382X

Karlyshev, Andrey V, Linton, Dennis, Gregson, Norman A and Wren, Brendan W (2002) A novel paralogous gene family involved in phase-variable flagella-mediated motility in Campylobacter jejuni.Microbiology, 148(2), pp. 473-480. ISSN (print) 1350-0872

Karlyshev, A V, Oyston, P C, Williams, K, Clark, G C, Titball, R W, Winzeler, E A and Wren, B W(2001) Application of high-density array-based signature-tagged mutagenesis to discover novel Yersinia virulence-associated genes. Infection and immunity, 69(12), pp. 7810-7819. ISSN (print) 0019-9567

Parkhill, J, Wren, B W, Thomson, N R, Titball, R W, Holden, M T, Prentice, M B, Sebaihia, M, James, K D, Churcher, C, Mungall, K L, Baker, S, Basham, D, Bentley, S D, Brooks, K, Cerdeño-Tárraga, A M,Chillingworth, T, Cronin, A, Davies, R M, Davis, P, Dougan, G, Feltwell, T, Hamlin, N, Holroyd, S,Jagels, K, Karlyshev, A V, Leather, S, Moule, S, Oyston, P C, Quail, M, Rutherford, K, Simmonds, M,Skelton, J, Stevens, K, Whitehead, S and Barrell, B G (2001) Genome sequence of Yersinia pestis, the causative agent of plague. Nature, 413(6855), pp. 523-527. ISSN (print) 0028-0836

Dorrell, N, Mangan, J A, Laing, K G, Hinds, J, Linton, D, Al-Ghusein, H, Barrell, B G, Parkhill, J, Stoker, N G, Karlyshev, A V, Butcher, P D and Wren, B W (2001) Whole genome comparison of Campylobacter jejuni human isolates using a low-cost microarray reveals extensive genetic diversity.Genome research, 11(10), pp. 1706-1715. ISSN (print) 1088-9051

Karlyshev, A V, McCrossan, M V and Wren, B W (2001) Demonstration of polysaccharide capsule in Campylobacter jejuni using electron microscopy. Infection and immunity, 69(9), pp. 5921-5924. ISSN (print) 0019-9567

Wren, B W, Linton, D, Dorrell, N and Karlyshev, A V (2001) Post genome analysis of Campylobacter jejuni. Symposium series (Society for Applied Microbiology), 90(S6), 36S-44S. ISSN (print) 1467-4734

Linton, D, Karlyshev, A V and Wren, B W (2001) Deciphering Campylobacter jejuni cell surface interactions from the genome sequence. Current opinion in microbiology, 4(1), pp. 35-40. ISSN (print) 1369-5274

Karlyshev, A V and Wren, B W (2001) Detection and initial characterization of novel capsular polysaccharide among diverse Campylobacter jejuni strains using alcian blue dye. Journal of clinical microbiology, 39(1), pp. 279-284. ISSN (print) 0095-1137

Karlyshev, A V, Pallen, M J and Wren, B W (2000) Single-primer PCR procedure for rapid identification of transposon insertion sites. BioTechniques, 28(6), pp. 1078-1082. ISSN (print) 0736-6205

Linton, D, Karlyshev, A V, Hitchen, P G, Morris, H R, Dell, A, Gregson, N A and Wren, B W (2000)Multiple N-acetyl neuraminic acid synthetase (neuB) genes in Campylobacter jejuni: identification and characterization of the gene involved in sialylation of lipo-oligosaccharide. Molecular microbiology, 35(5), pp. 1120-1134. ISSN (print) 0950-382X

Parkhill, J, Wren, B W, Mungall, K, Ketley, J M, Churcher, C, Basham, D, Chillingworth, T, Davies, R M, Feltwell, T, Holroyd, S, Jagels, K, Karlyshev, A V, Moule, S, Pallen, M J, Penn, C W, Quail, M A,Rajandream, M A, Rutherford, K M, van Vliet, A H, Whitehead, S and Barrell, B G (2000) The genome sequence of the food-borne pathogen 'Campylobacter jejuni' reveals hypervariable sequences. Nature, 403(6770), pp. 665-668. ISSN (print) 0028-0836

Karlyshev, A V, Linton, D, Gregson, N A, Lastovica, A J and Wren, B W (2000) Genetic and biochemical evidence of a Campylobacter jejuni capsular polysaccharide that accounts for Penner serotype specificity. Molecular microbiology, 35(3), pp. 529-541. ISSN (print) 0950-382X

Chapman, D A, Zavialov, A V, Chernovskaya, T V, Karlyshev, A V, Zav'yalova, G A, Vasiliev, A M,Dudich, I V, Abramov, V M, Zav'yalov, V P and MacIntyre, S (1999) Structural and functional significance of the FGL sequence of the periplasmic chaperone Caf1M of Yersinia pestis. Journal of bacteriology, 181(8), pp. 2422-2429. ISSN (print) 0021-9193

Mikhailov, AM, Chernovskaya, TV, Vasil'ev, AM, Rudenko, EG, Kornev, AN, Kornilov, VV, Karlyshev, AV, MacIntyre, S, Abramov, VM, Zav'yalov, VP and Vainshtein, BK (1999) Preparation of chromatographically pure specimens, crystallization, and X-ray diffraction study of the periplasmatic chaperone protein Caf1M from Y-pestis. Crystallography Reports, 44, pp. 1010-1013. ISSN (print) 1063-7745

Karlyshev, A V, Henderson, J, Ketley, J M and Wren, B W (1999) Procedure for the investigation of bacterial genomes: random shot-gun cloning, sample sequencing and mutagenesis of Campylobacter jejuni. BioTechniques, 26(1), pp. 50-56. ISSN (print) 0736-6205

Karlyshev, A V, Henderson, J, Ketley, J M and Wren, B W (1998) An improved physical and genetic map of Campylobacter jejuni NCTC 11168 (UA580). Microbiology, 144(2), pp. 503-508. ISSN (print) 1350-0872

Swift, S, Karlyshev, A V, Fish, L, Durant, E L, Winson, M K, Chhabra, S R, Williams, P, Macintyre, Sand Stewart, G S (1997) Quorum sensing in Aeromonas hydrophila and Aeromonas salmonicida: identification of the LuxRI homologs AhyRI and AsaRI and their cognate N-acylhomoserine lactone signal molecules. Journal of bacteriology, 179(17), pp. 5271-5281. ISSN (print) 0021-9193

Zav'yalov, V P, Chernovskaya, T V, Chapman, D A, Karlyshev, A V, MacIntyre, S, Zavialov, A V,Vasiliev, A M, Denesyuk, A I, Zav'yalova, G A, Dudich, I V, Korpela, T and Abramov, V M (1997)Influence of the conserved disulphide bond, exposed to the putative binding pocket, on the structure and function of the immunoglobulin-like molecular chaperone Caf1M of Yersinia pestis.Biochemical journal, 324 ( Pt 2), pp. 571-578. ISSN (print) 0264-6021

Chemovskaya, T V, Karlishev, Andrey, Navolotskaya, E V, Vasiliev, A M, Rudenko, E G, Abramov, V M, McIntyre, S H and Zav'yalov, V P (1997) Reception of human interleukin-1β by bacterial cells.Immunology Letters, 56, p. 211.

Karlyshev, A V and MacIntyre, S (1996) Study of the intergenic exeF-exeG region and its application as a simple preliminary test for Aeromonas spp. FEMS microbiology letters, 137(1), pp. 37-44. ISSN (print) 0378-1097

Karlyshev, A V and MacIntyre, S (1995) Cloning and study of the genetic organization of the exe gene cluster of Aeromonas salmonicida. Gene, 158(1), pp. 77-82. ISSN (print) 0378-1119

Zav'yalov, V P, Chernovskaya, T V, Navolotskaya, E V, Karlyshev, A V, MacIntyre, S, Vasiliev, A Mand Abramov, V M (1995) Specific high affinity binding of human interleukin 1 beta by Caf1A usher protein of Yersinia pestis. FEBS letters, 371(1), pp. 65-68. ISSN (print) 0014-5793

Drozdov, I G, Anisimov, A P, Samoilova, S V, Yezhov, I N, Yeremin, S A, Karlyshev, A V, Krasilnikova, V M and Kravchenko, V I (1995) Virulent non-capsulate Yersinia pestis variants constructed by insertion mutagenesis. Journal of medical microbiology, 42(4), pp. 264-268. ISSN (print) 0022-2615

Abramov, V, Chernovskaya, T, Vasiliev, A, Karlishev, Andrey, Navolotskaya, E and Zav'yalov, V(1994) Interaction of human interleukin 1-beta with Escherichia coli cells transformed by capsular f1 operon Yersinia pestis. Cytokine, 6(5), 552- 552. ISSN (print) 1043-4666

Drozdov, I.G., Ezhov, I.N., Samoilova, S.V., Anisimov, A.P., Karlyshev, A.V., Kravchenko , V.I.,Krasilnikova , V.M., Eremin , S.A. and Nikiforov , A.K. (1993) A method of generation of plague agent acapsular mutant. Problems of Particularly Dangerous Infections, 3 (73), pp. 187-194.

Karlyshev, A V, Galyov, E E, Abramov, V M and Zav'yalov, V P (1992) Caf1R gene and its role in the regulation of capsule formation of Y. pestis. FEBS letters, 305(1), pp. 37-40. ISSN (print) 0014-5793

Karlyshev, A V, Galyov, E E, Smirnov , O Yu, Guzayev, A P, Abramov, V M and Zav'yalov, V P (1992)A new gene of the f1 operon of Y. pestis involved in the capsule biogenesis. FEBS letters, 297(1-2), pp. 77-80. ISSN (print) 0014-5793

Galyov, E. E., Karlishev, Andrey, Chernovskaya, T. V., Dolgikh, D. A., Smirnov, O. Yu, Volkovoy, K. I., Abramov, V. M. and Zav′yalov, V. P. (1991) Expression of the envelope antigen F1 of Y. pestis is mediated by the product of caf1M gene having homology with chaperon protein PapD of E. coli.FEBS Letters, 286(1-2), pp. 79-82. ISSN (print) 0014-5793

Galyov, E E, Smirnov, O Y, Karlyshev, Andrey, Volkovoy, K I , Denesyuk, A I, Nazimov, I V, Rubtsov, K S, Abramov, V M, Dalvadyanz, S M and Zav'yalov, V P (1990) Nucleotide sequence of the Y. pestis gene encoding F1 antigen and the primary structure of the protein. FEBS Letters, 277(1-2), pp. 230-232. ISSN (print) 0014-5793

Deev, S.M., Chuvpilo, S.A., Karlyshev, A.V., Mukhamedov, R.S. and Polyanovskii, O.L. (1982)Analysis and properties of a bacterial clone containing a fragment of the Immuno Globulin L chain gene. Genetika, 18(6), pp. 888-895. ISSN (print) 0016-6758

Deev, S.M., Karlyshev, A.V. and Polyanovskii, O.L. (1982) Construction and selection of bacterial clones hybridized with immuno globulin light chain messenger RNA. Genetika, 18(6), pp. 880-887. ISSN (print) 0016-6758

Deev, S M, Chuvpilo, S A, Karlyshev, A V, Mukhamedov, R S and Polianovskiĭ, O L (1982) [Analysis and properties of a bacterial clone containing a gene fragment of an immunoglobulin L chain].Genetika, 18(6), pp. 888-895. ISSN (print) 0016-6758

Deev, S M, Karlyshev, A V and Polianovskiĭ, O L (1982) [Construction and selection of bacterial clones hybridized with the mRNA of a light-chain immunoglobulin]. Genetika, 18(6), pp. 880-887. ISSN (print) 0016-6758

Dejev, S., Muhamedov, R., Karlyshev, A., Aslanov, H. and Sadykov, A. (1982) Stability of DNA fragments of bacteriophage lambda cloned in E. coli using pBR322 vector. Reports of Academy of Science of Uzbek SSR, 1, pp. 45-48. ISSN (print) 0134-4307

Deev, S M, Karlyshev, A V and Polianovskiĭ, O L (1981) [Identification of a bacterial clone containing a fragment of the structural portion of an immunoglobulin light-chain gene]. Doklady Akademii nauk SSSR, 257(6), pp. 1481-3. ISSN (print) 0002-3264

Deev, S M, Mukhamedov, R S , Karlyshev, Andrey, Denisova, G F and Aslanov, K H A (1981) A modified crude lysate method for hybrid plasmid analysis. Uzbekskii Biologicheskii Zhurnal (in Russian), 6, pp. 9-12. ISSN (online) 0024-1685

Deev, S M, Barbakar', N I, Karlyshev, A V, Sakharova, N K and Grechko, V V (1980) [Synthesis of double-stranded DNA on light immunoglobulin chain matrix RNA]. Molekulyarnaya biologiya, 14(2), pp. 413-420. ISSN (print) 0026-8984

Deev, S M, Barkabar', N I, Karlyshev, A V, Grechko, V V and Polianovskiĭ, O L (1979) [Enzymatic synthesis of the structural gene of MORC-21 myeloma immunoglobulin light chains]. Doklady Akademii nauk SSSR, 248(2), pp. 469-471. ISSN (print) 0002-3264

Polyanovsky, O L, Nosikov, V V, Zhuze, A L, Braga, E A and Karlyshev, A V (1979) Regulation of restriction endonuclease activity with antibiotics. Advances in enzyme regulation, 17, pp. 307-321. ISSN (print) 0065-2571

Nosikov, V V, Braga, E A, Karlyshev, Andrey, Zhuze, A L and Polyanovsky , O L (1976) Protection of particular cleavage sites of restriction endonucleases by DstA and AcD. Nucleic Acids Research, 3(9), pp. 2293-2301. ISSN (print) 0305-1048

Polianovskiĭ, O L, Karlyshev, A V, Braga, E A and Nosikov, V V (1976) [Mapping of phage lambda DNA using the antibiotic distamycin]. Doklady Akademii nauk SSSR, 229(2), pp. 500-503. ISSN (print) 0002-3264

Book sections:

Karlyshev, Andrey, Wren, Brendan W and Moran, Anthony P (2008) Campylobacter jejuni Capsular Polysaccharide. In: Nachamkin , Irving , Szymanski, Christine M. and Blaser , Martin J. , (eds.)Campylobacter. 3rd edition. Washington, DC, USA : American Society for Microbiology Press,. pp. 505-522. ISBN 9781555814373

Karlyshev, Andrey, Champion, O L, Joshua, G W P and Wren, B W (2005) The polysaccharide capsule of Campylobacter jejuni. In: Ketley, J M and Konkel , M E , (eds.) Campylobacter: Molecular and Cellular Biology. Horizon Bioscience. pp. 249-258. ISBN 190493305X

Tereshin , S., Kulikova , N., Sakulin, V., Puchkova, G., Vasilenko, R., Vasiliev, A., Kosarev, I.,Khlebnikov, V., Karlyshev, A., Uversky, V. and Abramov, V. (2004) Pathogenetic role of minimal building blocks of 'Yersinia pestis' capsule: Caf1 dimers on early and late stages of pneumonic plague. In: O'Neill, Luke, (ed.) Procceedings of the International Cytokine Society Annual meeting.Bologna, Italy : Medimond Publishing. pp. 151-156. ISBN 9788875870133

Oyston, Petra C F, Karlyshev, Andrey V, Wren, Brendan W and Titball, Richard W (2003) Signature-tagged mutagenesis of Yersinia pestis. In: Skurnik, Mikael , Bengoechea, Jose Antonio and Granfors, Kaisa, (eds.) The Genus Yersinia: Entering the Functional Genomic Era. New York, USA : Kluwer Academic. pp. 39-42. (Advances in Experimental Medicine and Biology) ISSN (print) 0065-2598 ISBN 9780306477591

Karlyshev, Andrey (2003) Structural base of the polyfunctional role of Caf1 protein and Caf1M chaperone in providing Yersinia pestis circulation in ecological systems of natural plague foci. In:Uversky, Vladimir N., (ed.) Protein Structures: Kaleidoscope of Structural Properties and Function.Kerala, India. : Research Signpost. ISBN 8177361775

Karlyshev, A.V., Dorrell, N., Winzeler, E. and Wren, B.W. (2002) Further strategies for signature-tagged mutagenesis and the application of oligonucleotide microarrays for the quantification of DNA-tagged strains. In: Wren, Brendan and Dorrell, Nick, (eds.) Functional Microbial Genomics. London : Academic Press. pp. 167-184. (Methods in Microbiology, no. 33) ISSN (print) 0580-9517 ISBN 9780125215336

Karlyshev, A., Galyov, E., Smirnov, O. and Zav'yalov, V. (1994) Structure and regulation of a gene cluster involved in capsule formation of Yersinia pestis. In: Op den Kamp, Jos A. F., (ed.) Biological Membranes: Structure, Biogenesis and Dynamics. Berlin, Germany : Springer-Verlag. pp. 321-330. (NATO ASI series: Cell biology, no. 82) ISBN 9783540577317

Anisimov, A., Karlyshev, A., Pavlov, V. and Kravchenko, V. (1991) Construction of recombinant plasmids stably maintained in Y. pestis. In: Anisimov, A., (ed.) Genetics, Microbiology and Enhancement of Laboratory Diagnostics Methods of Particularly Dangerous Infections. Saratov, Russia : Federal state Public Health Russian reasearch anti "germs" institute "Microb". pp. 18-25.

Anisimov, A., Karlyshev, A., Kravchenko, V., Krasilnikova, V. and Kokushkin, A. (1991) Generation of avirulent Fra+, V+, Cad+, Fib-Coa+, PstI+, Psb+ mutants of Y. pestis. In: Anisimov, A., (ed.)Genetics, Microbiology and Enhancement of Laboratory Diagnostics Methods of Particularly Dangerous Infections. Saratov, Russia : Federal state Public Health Russian reasearch anti "germs" institute "Microb". pp. 29-33.

Conference Highlights

Professor Karlyshev is a seasoned conference presenter and has spoken around the world on his specialist subject.

Professional Body Membership

  • Fellow of Higher Education Academy
  • American Society of Microbiology
  • The Higher Education Academy, UK
  • Society for General Microbiology

Academic Accolades

  • The Welcome Trust Value in People Award

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Contact us

General enquiries:

Journalists only:

  • Communications team
    Tel: +44 (0)20 8417 3034
    Email us
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