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Dr Sianne Schwikkard

Senior Lecturer

About

I completed my PhD in Natural Products Chemistry at the University of Kwazulu-Natal, South Africa in 1998.  This was followed by a number of post-doctoral positions at Virginia Tech, the Rand Academic University and Kingston University.  In addition I spent some 18 months working in industry for Sasol Technology. 

After 11 years as a part-time lecturer, I joined Kingston University full time in September 2015.

Areas of specialism

  • Natural products Chemistry
  • Synthetic Organic Chemistry

Qualifications

  • PhD
  • MSc
  • BSc (hons)
  • BSc

Professional membership

I am a member of the Royal Society of Chemistry and a Fellow of the Higher Education Academy.

Research

I have an interest in bioactive natural products, both isolated from plant sources as well as their synthetic analogues. I have a particular interest in compounds known as homoisoflavonoids, isolated primarily from the Hyacinthaceae (Asparagaceae).  These compounds have a range of interesting biological activities including anti-cancer, anti-inflammatory and anti-angiogenic effects.  they have been identified as potential new sources of treatment for macular degeneration and I am working together with the University of Surrey and the Glick Eye Institute in this regard.

Publications

Number of items: 14.

Article

Aldhaher, Areej, Langat, Moses, Ndunda, Beth, Chirchir, Denis, Midiwo, Jacob O., Njue, Alice, Schwikkard, Sianne, Carew, Mark and Mulholland, Dulcie (2017) Diterpenoids from the roots of 'Croton dichogamus' Pax. Phytochemistry, 144, pp. 1-8. ISSN (print) 0031-9422

Schwikkard, Sianne, Alqahtani, Alaa, Knirsch, Walter, Wetschnig, Wolfgang, Jaksevicius, Andrius, Opara, Elizabeth, Langat, Moses, Andriantiana, Jackie and Mulholland, Dulcie (2017) Phytochemical investigations of three Rhodocodon (Hyacinthaceae Sensu APG II) species. Journal of Natural Products, 80(1), pp. 30-37. ISSN (print) 0163-3864

Schwikkard, Sianne L. and Mulholland, Dulcie A. (2014) Useful Methods for Targeted Plant Selection in the Discovery of Potential New Drug Candidates. Planta Medica, 80(14), pp. 1154-1160. ISSN (print) 0032-0943

Mulholland, Dulcie A., Schwikkard, Sianne L. and Crouch, Neil R. (2013) The chemistry and biological activity of the Hyacinthaceae. Natural Product Reports, 30(9), pp. 1165-1210. ISSN (print) 0265-0568

Morgan, David H., Schwikkard, Sianne L., Dixon, John T., Nair, Jerald J. and Hunter, Roger (2003) The Effect of Aromatic Ethers on the Trimerisation of Ethylene using a Chromium Catalyst and Aryloxy Ligands. Advanced Synthesis & Catalysis, 345(8), pp. 939-942. ISSN (print) 1615-4150

Morgan, David H., Schwikkard, Sianne L., Dixon, John T., Nair, Jerald J. and Hunter, Roger (2003) The effect of aromatic ethers on the trimerisation of ethylene using a chromium catalyst and aryloxy ligands. Advanced Synthesis & Catalysis, 345(8), pp. 939-942. ISSN (print) 1615-4150

Schwikkard, Sianne and van Heerden, Fanie R. (2002) Antimalarial activity of plant metabolites. Natural Product Reports, 19(6), pp. 675-692. ISSN (print) 0265-0568

Schwikkard, Sianne, Zhou, Bing-Nan, Glass, Thomas E., Sharp, Jessica L., Mattern, Michael R., Johnson, Randall K. and Kingston, David G. I. (2000) Bioactive Compounds from Combretum erythrophyllum. Journal of Natural Products, 63(7), pp. 1045-1046. ISSN (print) 0163-3864

Schwikkard, Sianne, Zhou, Bing-Nan, Glass, Thomas E., Sharp, Jessica L., Mattern, Michael R., Johnson, Randall K. and Kingston, David G. I. (2000) Bioactive Compounds from Combretum erythrophyllum. Journal of Natural Products, 63(4), pp. 457-460. ISSN (print) 0163-3864

Mulholland, Dulcie A., Schwikkard, Sianne L., Sandor, Peter and Nuzillard, Jean M. (2000) Delevoyin C, a tetranortriterpenoid from Entandrophragma delevoyi. Phytochemistry, 53(4), pp. 465-468. ISSN (print) 0031-9422

Mulholland, Dulcie A., Randrianarivelojosia, Milijaona, Lavaud, Catherine, Nuzillard, Jean-Marc and Schwikkard, Sianne L. (2000) Limonoid derivatives from Astrotrichilia voamatata. Phytochemistry, 53(1), pp. 115-118. ISSN (print) 0031-9422

Mulholland, Dulcie A., Schwikkard, Sianne L. and Randrianarivelojosia, Milijaona (1999) Limonoids from Astrotrichilia voamatata. Phytochemistry, 52(4), pp. 705-707. ISSN (print) 0031-9422

Schwikkard, Sianne L., Mulholland, Dulcie A. and Hutchings, Anne (1998) Phaeophytins from Tapura fischeri. Phytochemistry, 49(8), pp. 2391-2394. ISSN (print) 0031-9422

Conference or Workshop Item

Schwikkard, S., James, E. E., Mulholland, D. A., Knirsch, W., Corson, T., Opara, E. and Jaksevicius, A. (2015) Novel, bioactive homoisoflavonoids from a Madagascan Rhodocodon species (Hyacinthaceae, sensu APG II). In: 63rd International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA2015); 23 - 27 Aug 2015, Szeged, Hungary. (Unpublished)

This list was generated on Mon Dec 11 04:53:37 2017 GMT.
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