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Professor Mark Fielder

Professor of Medical Microbiology

About

I was awarded a PhD in  Microbiology and Immunology from Kings College London in 1995 winning the Tadion-Rideal Prize for outstanding postgraduate work. I then undertook Postdoctoral position at St Georges Hospital London on mucosal vaccination against Vibrio cholerae. After joining Kingston University as a lecturer (1998) in medical Microbiology and awarded a chair in Medical Microbiology in 2011. I  act as an advisor for the Clinical Laboratory Sciences Institute (Veterinary antimicrobial susceptibility testing) and sit on the Parliamentary and Scientific committee. My research team are multidisciplinary working on rapid detection systems for infectious disease diagnosis and to overcome antimicrobial resistance in clinical and veterinary settings and looking at antibiotic overspill into wild raptors. I am currently the President of the Society for Applied Microbiology

Areas of specialism

  • Rapid detection of Microorganisms
  • Medical and Veterinary microbiology
  • Antiobiotic resistance
  • Public engagement
  • Antibiotic resistance/ Infection Spillover
  • One Health

Media enquiries

Journalists who would like to arrange interviews with the University's academic experts should contact the Communications team.

Qualifications

  • PGCTLHE/FHEA
  • Tadion Rideal Prize for outstanding Doctoral Work, Kings College London
  • PhD, Kings College London
  • BSc Microbiology, Kings College London

Professional membership

I am a member and current president of the Society for Applied Microbiology, I am a member of the Clinical Laboratory Sciences Institute (CLSI) and a member of the Institute for Biomedical Sciences (IBMS).

Research

My research group has a generally broad scope but all under the one health banner. We are involved in trying to understand how bacteria mutate in the face of different selective pressures as a result of antibiotic pressure. We are looking at the discovery of novel antibiotics from different environmental niches and we are looking at the development of novel and rapid diagnostics that can be used in both human and animal health to facilitate early identification of pathogens  and so appropriate and targeted treatment with anti-infectives. This approach also helps in the stewardship and protection of antibiotics. We are looking at antibiotic resistance spillover into wild raptor populations with the Sussex Peregrine Study Group. 

We are also working with the veterinary and farming communities to understand antimicrobial resistance using both traditional laboratory science as well as social science to understand the publics perception of antibiotic use and benefits.

Publications

Number of items: 43.

Article

Bywaters, Luke, Mulcahy-Ryan, Lauren, Fielder, Mark, Sinclair, Alex and Le Gresley, Adam (2017) Synthetic scale-up of a novel fluorescent probe and its biological evaluation for surface detection of 'Staphylococcus aureus'. Molecular and Cellular Probes, ISSN (print) 0890-8508 (Epub Ahead of Print)

Holloway, A. C., Mueller-Harvey, I., Gould, S. W. J., Fielder, M. D., Naughton, D. P. and Kelly, A. P. (2015) Heat treatment enhances the plant phenolic (+)-catechin, a weak antimicrobial agent when combined with copper sulphate. Letters in Applied Microbiology, 61(4), pp. 381-389. ISSN (print) 0266-8254

Wedley, Amy L, Dawson, Susan, Maddox, Thomas W, Coyne, Karen P, Pinchbeck, Gina L, Clegg, Peter, Jamrozy, Dorota, Fielder, Mark D., Donovan, David, Nuttall, Tim and Williams, Nicola J (2014) Carriage of Staphylococcus species in the veterinary visiting dog population in mainland UK: Molecular characterisation of resistance and virulence. Veterinary Microbiology, 170(1-2), pp. 81-88. ISSN (print) 0378-1135

Stokes, M.O., AbuOun, M., Umur, S., Wu, G., Partridge, S. R., Mevius, D. J., Coldham, N. G. and Fielder, M. D. (2013) Complete Sequence of pSAM7, an IncX4 Plasmid Carrying a Novel bla[sub]CTX-M-14b Transposition Unit Isolated from ' Escherichia coli ' and ' Enterobacter cloacae ' from cattle. Antimicrobial Agents and Chemotherapy, 57(9), pp. 4590-4594. ISSN (print) 0066-4804

Sinclair, Alex, Mulcahy, Lauren, Geldeard, Lynsey, Malik, Samerah, Fielder, Mark and Le Gresley, Adam (2013) Development of an in situ culture-free screening test for the rapid detection of Staphylococcus aureus within healthcare environments. Organic & Biomolecular Chemistry, 11(20), pp. 3307-3313. ISSN (print) 1477-0520

Epstein, Jonathan H, Baker, Michelle L, Zambrana-Torrelio, Carlos, Middleton, Deborah, Barr, Jennifer A, Dubovi, Edward, Boyd, Victoria, Pope, Brian, Todd, Shawn, Crameri, Gary, Walsh, Allyson, Pelican, Katey, Fielder, Mark D, Davies, Angela J, Wang, Lin-Fa and Daszak, Peter (2013) Duration of maternal antibodies against canine distemper virus and hendra virus in pteropid bats. PloS One, 8(6), e67584. ISSN (online) 1932-6203

Khatri, Bhagwati, Fielder, Mark, Jones, Gareth, Newell, William, Abu-Oun, Manal and Wheeler, Paul.R. (2013) High throughput phenotypic analysis of 'Mycobacterium tuberculosis' and 'Mycobacterium bovis' strains' metabolism using Biolog Phenotype Microarrays. PLOS ONE, 8(1), e52673. ISSN (online) 1932-6203

Jamrozy, Dorota M., Fielder, Mark D., Butaye, Patrick, Coldham, Nick G. and , (2012) Comparative genotypic and phenotypic characterisation of methicillin-resistant staphylococcus aureus ST398 isolated from animals and humans. PLoS ONE, 7(7), e40458. ISSN (print) 1932-6203

Stokes, M. O., Cottell, J. L., Piddock, L. J. V., Wu, G., Wootton, M., Mevius, D. J., Randall, L. P., Teale, C. J., Fielder, M. D. and Coldham, N. G. (2012) Detection and characterization of pCT-like plasmid vectors for blaCTX-M-14 in Escherichia coli isolates from humans, turkeys and cattle in England and Wales. Journal of Antimicrobial Chemotherapy, 67(7), pp. 1639-1644. ISSN (print) 0305-7453

Phillips, C.A., Gkatzionis, K., Laird, K., Score, J., Kant, A. and Fielder, M.D. (2012) Identification and quantification of the antimicrobial components of a citrus essential oil vapor. Natural Product Communications, 7(1), pp. 103-107. ISSN (print) 1934-578X

Spencer-Smith, Russell, Varkey, Eldho, Fielder, Mark and Snyder, Lori (2012) Sequence features contributing to chromosomal rearrangements in 'Neisseria gonorrhoeae'. PLOS One, 7(9), e46023. ISSN (online) 1932-6203

Gresley, Adam le, Kenny, Jackie, Cassar, Claire, Kelly, Alison, Sinclair, Alex and Fielder, Mark D (2012) The application of high resolution diffusion NMR to the analysis of manuka honey. Food Chemistry, 135(4), pp. 2879-86. ISSN (print) 0308-8146

Holloway, Andrew, Mueller-Harvey, Irene, Gould, Simon W. G., Fielder, Mark D., Naughton, Declan P. and Kelly, Alison F. (2012) The effect of copper(ii), iron(ii) sulphate, and vitamin C combinations on the weak antimicrobial activity of (+)-catechin against Staphylococcus aureus and other microbes. Metallomics : integrated biometal science, 4(12), pp. 1280-1286. ISSN (print) 1756-5901

Al-Azemi, Ahmed, Fielder, Mark D, Abuknesha, Ramadan A. and Price, Robert G. (2011) Effects of chelating agent and environmental stresses on microbial biofilms: relevance to clinical microbiology. Journal Of Applied Microbiology, 110(5), pp. 1307-1313. ISSN (print) 1364-5072

Holloway, Andrew C., Gould, Simon W. J., Fielder, Mark D., Naughton, Declan P. and Kelly, Alison F (2011) Enhancement of antimicrobial activities of whole and sub-fractionated white tea by addition of copper (II) sulphate and vitamin C against 'Staphylococcus aureus'; a mechanistic approach. BMC Complementary and Alternative Medicine, 11(1), p. 115. ISSN (online) 1472-6882

Money, P., Kelly, A.F., Gould, S.W.J, Denholm-Price, J., Threlfall, E.J. and Fielder, M. (2010) Cattle, weather and water: mapping Escherichia coli O157:H7 infections in humans in England and Scotland. Environmental Microbiology, 12(10), pp. 2633-2644. ISSN (print) 1462-2912

Mboto, C. I., Fielder, M., Davies-Russell, Angela and Jewell, A. (2010) Hepatitis C virus prevalence and serotypes associated with HIV in The Gambia. British Journal of Biomedical Science, 67(3), pp. 140-144. ISSN (print) 0967-4845

Gould, Simon WJ, Cuschieri, Paul, Rollason, Jess, Hilton, Anthony C, Easmon, Sue and Fielder, Mark D (2010) The need for continued monitoring of antibiotic resistance patterns in clinical isolates of Staphylococcus aureus from London and Malta. Annals of Clinical Microbiology and Antimicrobials, 9(20), ISSN (online) 1476-0711

Gould, Simon WJ, Fielder, Mark D, Kelly, Alison F and Naughton, Declan P (2009) Anti-microbial activities of pomegranate rind extracts: enhancement by cupric sulphate against clinical isolates of S. aureus, MRSA and PVL positive CA-MSSA. BMC Complementary and Alternative Medicine, 9(23), ISSN (online) 1472-6882

Gould, S W J, Fielder, M D, Kelly, A F, El Sankary, W and Naughton, D P (2009) Antimicrobial pomegranate rind extracts: enhancement by Cu(II) and vitamin C combinations against clinical isolates of Pseudomonas aeruginosa. British Journal of Biomedical Science, 66(3), pp. 129-132. ISSN (print) 0967-4845

Afshar, B., Nicholas, R.A.J., Pitcher, D., Fielder, M.D. and Miles, R.J. (2009) Biochemical and genetic variation in Mycoplasma fermentans strains from cell line, human and animal sources. Journal Of Applied Microbiology, 107(2), pp. 498-505. ISSN (print) 1364-5072

Mboto, CI, Davies-Russell, A, Fielder, M and Jewell, A P (2009) CD4+ lymphocyte values and trends in individuals infected with Human Immunodeficiency Virus and/or co-infected with Hepatitis C virus in The Gambia. African Health Sciences, 9(3), pp. 130-136. ISSN (print) 1680-6905

Mboto, C.I., Fielder, Mark, Davies-Russell, Angela and JEWELL, ANDREW (2009) Prevalence of HIV-1, HIV-2, hepatitis C and co-infection in The Gambia. West African Journal of Medicine, 28(1), pp. 306-309. ISSN (print) 0189-160X

Thompson, Richard, Bidgood, Penelope, Petroczi, Andrea, Denholm-Price, James C.W. and Fielder, Mark D. (2009) An alternative methodology for the prediction of adherence to anti HIV treatment. AIDS Research and Therapy, 6(9), ISSN (online) 1742-6405

Gould, Simon W. J., Fielder, Mark D., Kelly, Alison F., Morgan, Marina, Kenny, Jackie and Naughton, Declan P. (2009) The antimicrobial properties of copper surfaces against a range of important nosocomial pathogens. Annals of Microbiology, 59(1), pp. 151-156. ISSN (print) 1590-4261

Gould, Simon W J, Chadwick, Maureen, Cuschieri, Paul, Easmon, Susan, Richardson, Anthony C, Price, Robert G and Fielder, Mark D (2009) The evaluation of novel chromogenic substrates for the detection of lipolytic activity in clinical isolates of Staphylococcus aureus and MRSA from two European study groups. FEMS Microbiology Letters, 297(1), pp. 10-16. ISSN (print) 0378-1097

McCarrell, Erin M, Gould, Simon WJ, Fielder, Mark D, Kelly, Alison F, El Sankary, Waffa and Naughton, Declan P (2008) Antimicrobial activities of pomegranate rind extracts: enhancement by addition of metal salts and vitamin C. BMC Complementary and Alternative Medicine, 8(64), pp. 1-7. ISSN (online) 1472-6882

Thompson, R.I., Bidgood, P., Petroczi, A., Denholm-Price, J. and Fielder, M. (2008) Statistical analysis of HIV-patient data from central Europe: lessons from a three-centre study. European Infectious Disease, 2(1), pp. 52-56.

Gould, Simon W J, Rollason, Jess, Hilton, Anthony C, Cuschieri, Paul, McAuliffe, Laura, Easmon, Susan L and Fielder, Mark D (2008) UK epidemic strains of meticillin-resistant Staphylococcus aureus in clinical samples from Malta. Journal of Medical Microbiology, 57(11), pp. 1394-1398. ISSN (print) 0022-2615

Patel, Hiren, Mackintosh, David, Ayling, Roger D., Nicholas, Robin A. J. and Fielder, Mark D. (2008) A novel medium devoid of ruminant peptone for high yield growth of Mycoplasma ovipneumoniae. Veterinary Microbiology, 127(3-4), pp. 309-314. ISSN (print) 0378-1135

Stokes, David J., Kelly, Alison F., Gould, Simon W. J., Cassar, Claire A. and Fielder, Mark D. (2008) The withdrawal of antimicrobial treatment as a mechanism for defeating resistant microorganisms. FEMS Immunology & Medical Microbiology, 53(3), pp. 300-305. ISSN (print) 0928-8244

Coffils, M., Jewell, A.P., Jones, L.A. and Fielder, M.D. (2007) Induction of oxidative DNA damage by Helicobacter pylori in HT29 cells. British Journal of Biomedical Science, 64(4), pp. 149-152. ISSN (print) 0967-4845

Mboto, C.I., Davies, A., Fielder, M. and Jewell, A.P. (2006) Human immunodeficiency virus and hepatitis C co-infection in sub-Saharan West Africa. British Journal of Biomedical Science, 63(1), pp. 29-37.

Khan, Liaqat Ali, Loria, Guido R., Ramirez, Anna Sofia, Nicholas, Robin A.J., Miles, Roger J. and Fielder, Mark D. (2005) Biochemical characterisation of some non fermenting, non arginine hydrolysing mycoplasmas of ruminants. Veterinary Microbiology, 109(1-2), pp. 129-134. ISSN (print) 0378-1135

Mboto, C.I., Davies-Russell, A., Fielder, M. and Jewell, A.P. (2005) Hepatitis C antibodies in asymptomatic first-time blood donors in The Gambia: prevalence and risk factors. British Journal of Biomedical Science, 62(2), pp. 89-91. ISSN (print) 0967-4845

Blankenberg-Sprenkels, S H, Fielder, M, Feltkamp, T E, Tiwana, H, Wilson, C and Ebringer, A (1998) Antibodies to Klebsiella pneumoniae in Dutch patients with ankylosing spondylitis and acute anterior uveitis and to Proteus mirabilis in rheumatoid arthritis. Journal of Rheumatology, 25(4), pp. 743-747. ISSN (print) 0315-162X

Fielder, M and Lewis, D J M (1998) Vaccination against bacterial gut infections. Current Opinion in Infectious Diseases, 11(5), pp. 591-596. ISSN (print) 0951-7375

Tani, Y, Tiwana, H, Hukuda, S, Nishioka, J, Fielder, M, Wilson, C, Bansal, S and Ebringer, A (1997) Antibodies to Klebsiella, Proteus, and HLA-B27 peptides in Japanese patients with ankylosing spondylitis and rheumatoid arthritis. Journal of Rheumatology, 24(1), pp. 109-114. ISSN (print) 0315-162X

Ebringer, A, Ahmadi, K, Fielder, M, Rashid, T, Tiwana, H, Wilson, C, Collado, A and Tani, Y (1996) Molecular mimicry: the geographical distribution of immune responses to Klebsiella in ankylosing spondylitis and its relevance to therapy. Clinical Rheumatology, 15(Suppleme), pp. 57-61. ISSN (print) 0770-3198

Conference or Workshop Item

Epstein, J.H., Anthony, S.J., Islam, A., Kilpatrick, A.M., Khan, S. Ali, Ross, N., Smith, I., Barr, J., Zambrana-Torrelio, C., Tao, Y., Islam, A., Quan, P.L., Olival, K., Gurley, E., Hossain, M.J., Field, H.E., Fielder, M., Briese, T., Rahman, M., Crameri, G., Wang, L.-F., Luby, S., Lipkin, W.I. and Daszak, P. (2016) Nipah virus ecology and infection dynamics in its bat reservoir, 'Pteropus medius', in Bangladesh. In: International Meeting on Emerging Diseases and Surveillance (IMED) 2016; 04-07 Nov 2016, Vienna, Austria. (Unpublished)

Hills, Daniel, Mohseni, Maria, Dowler, Jan, Greenwood, Iain, Fielder, Mark, Pearson, Russell and Perumal, Dhaya (2014) Antihypertensive and antibacterial investigations of novel nitric oxide donor compounds. In: 8th International conference on the biology, chemistry and therapetic application of Nitric Oxide; 16-20 June, 2014, Cleveland, Ohio, U.S.A.. ISSN (print) 1089-8611

Bidgood, Penelope, Denholm-Price, James, Fielder, Mark, Petróczi, Andrea and Thompson, Richard (2007) Predicting Response to Antiretroviral Treatments in HIV Patients - the EuResist Project. In: Statistics in Public Policy-Making: Hope vs. Reality; 16 -20 Jul 2007, York, U.K..

Patent

Sinclair, Alex [Inventor], Fielder, Mark [Inventor] and Le Gresley, Adam [Inventor] (2013) Kingston University Higher Education Corporation Rhodamine based fluorescent probe for coagulase activity and detection of coagulase producing bacterial strains. WO 2014013272 A1.

This list was generated on Thu Sep 21 04:42:00 2017 BST.
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