Miss Aya M. Mostafa

Research project: Development of molecularly imprinted polymers (MIPs) assisted sensitive analytical methodologies for detection and monitoring of fungal infections biomarkers

Abstract

Development of rapid, simple and sensitive analytical methodologies based on Molecular Imprinted Polymers (MIP) for detection and quantification of fungal infection biomarkers (galactomannan and 1,3-β-D glucan) in different clinical samples and to optimize and validate the developed methods to reach the designated performance criteria. The study will go on to apply the developed methods for detection of these biomarkers in invasive fungal infections in patients.

  • Research degree: PhD
  • Title of project: Development of molecularly imprinted polymers (MIPs) assisted sensitive analytical methodologies for detection and monitoring of fungal infections biomarkers
  • Research supervisor: Dr James Barker
  • Other research supervisor: Dr Stephen Barton

Biography

I had my Bsc degree in pharmaceutical sciences in 2013 from faculty of pharmacy, Assiut university, Egypt. I got hired by the university as a demonstrator in same year of graduation. I did my masters in pharmaceutical sciences (pharmaceutical analytical chemistry) in 2018 and i was hired afterwards as an assistant lecturer in Faculty of pharmacy, Assiut university, Egypt. Now i am PhD student at kingston university with my research focus on biomarkers and molecularly imprinted polymers as an effective tool of extraction and analysis.

Areas of research interest

  • Analytical chemistry
  • Drug analysis
  • Methods of extraction
  • Body fluids analysis
  • Chromatography
  • Molecularly imprinted polymers
  • biomarkers and biosensors

Qualifications

  • Bsc (Hons.) in pharmaceutical sciences , 2013, Faculty of pharmacy, Assiut university, Egypt.
  • Msc in Pharmaceutical analytical chemistry, 2018, Faculty of pharmacy, Assiut university, Egypt.

Funding or awards received

  • Newton-Mosharafa full PhD scholarship

Publications

1- F.A. Mohamed, M.F.B. Ali, Highly sensitive UHPLC – DAD method for simultaneous determination of two synergistically acting antiepileptic drugs; levetiracetam and lacosamide: Application to pharmaceutical tablets and human urine, Biomed. Chromatogr. (2019) 1–11. doi:10.1002/bmc.4554.

2- F. A. Mohamed, M. F. B. Ali, A. H. Rageh, and A. M. Mostafa, "A highly sensitive HPTLC method for estimation of oxcarbazepine in two binary mixtures with two metabolically related antiepileptic drugs: Application to pharmaceutical and biological samples," Microchem. J., vol. 146, pp.414–422, 2019.

3- A. M. Mostafa, A. H. Rageh, M. F. B. Ali, and F. A. Mohamed, "Micelle and inclusion complex enhanced spectrofluorimetric methods for determination of Retigabine: Application in pharmaceutical and biological analysis," Spectrochim. Acta - Part A Mol. Biomol. Spectrosc., vol. 207,pp. 251–261, 2019.

4- F. A. Mohamed, M. F. Bakr, A. H. Rageh, and A. M. Mostafa, "The use of separationtechniques in the analysis of some antiepileptic drugs: A critical review," J. Liq. Chromatogr. Relat.Technol., vol. 39, no. 17–18, pp. 783–798, 2016.