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Dr Mark Carew

Associate professor in Physiology and Pharmacology

About

I'm a cell biologist and physiologist, and fascinated by how cells and the human body work. I teach these subjects, mostly on the Pharmacy course. I favour active learning methods, such as the use of computer simulations and a more workshop style, student-centred and collaborative approach in lectures.  Recently I have developed interactive stories for teaching science: www.climbingthepyramid.com 

My lab-based research had many angles. e.g. mechanisms of how plant-derived chemicals reduce the growth of cancer and other cells.  Now my interests are more physiological, with current research on blood pressure regulation, and in particular the osmopressor response (water ingestion transiently lowers heart rate in healthy volunteers).

I did my first degree in Biochemistry at King's College, London, my PhD in Cell Physiology at Cambridge, and then six years post-doctoral research at Cambridge and in the USA.  After a few years as a medical writer, I joined Kingston in 2005.

Areas of specialism

  • Physiology
  • Cell biology
  • Interactive stories to teach science
  • Personal tutor support

Qualifications

  • PhD Cambridge, Cell Physiology
  • BSc Biochemistry with Physiology, King's College London

Professional membership

Member, Physiological Society

Research

Poster PCA006 Investigation of the osmopressor response in young healthy adults

Mark Carew

Europhysiology 2018, London

Using a word game to test physiology comprehension

Mark Carew

Advances in Physiology Education 2018 42:3, 464-465 

Research student supervision

Publications

Number of items: 18.

Article

Maccabe, Rebecca, Micallef, Ricarda and Carew, Mark (2019) Peer-assisted learning to support attainment in Pharmacy. Compass: Journal of Learning and Teaching, 12(1), ISSN (print) 2044-0073

Easa, Najma, Alany, Raid G., Carew, Mark and Vangala, Anil (2018) A review of non-invasive insulin delivery systems for diabetes therapy in clinical trials over the past decade. Drug Discovery Today, ISSN (print) 1359-6446 (Epub Ahead of Print)

Carew, Mark (2018) Using a word game to test physiology comprehension. Advances in Physiology Education, 42(3), pp. 464-465. ISSN (print) 1043-4046

Schwikkard, Sianne, Whitemore, Hannah, Corson, Timothy, Sishtla, Kamakshi, Langat, Moses K., Carew, Mark and Mulholland, Dulcie A. (2018) Antiangiogenic activity and cytotoxicity of triterpenoids and homoisoflavonoids from 'Massonia pustulata' and 'Massonia bifolia'. Planta Medica, 84, pp. 638-644. ISSN (print) 0032-0943

Jaksevicius, Andrius, Carew, Mark, Mistry, Calli, Modjtahedi, Helmout and Opara, Elizabeth I (2017) Inhibitory effects of culinary herbs and spices on the growth of HCA-7 colorectal cancer cells and their COX-2 expression. Nutrients, 9(10), ISSN (online) 2072-6643

Abdelkader, H., Pierscionek, B., Carew, M., Wu, Z. and Alany, R.G. (2015) Critical appraisal of alternative irritation models: three decades of testing ophthalmic pharmaceuticals. British Medical Bulletin, 113(1), pp. 59-71. ISSN (print) 0007-1420

Waheed, A., Ludtmann, M.H.R., Pakes, N., Robery, S., Kuspa, A., Dinh, C., Baines, D., Williams, R.S.B. and Carew, M. (2014) Naringenin inhibits the growth of Dictyostelium and MDCK-derived cysts in a polycystin-2 (TRPP2)-dependent manner. British Journal of Pharmacology, 171(10), pp. 2659-2670. ISSN (print) 0007-1188

Polycarpou, Elena, Meira, Lisiane B, Carrington, Simon, Tyrrell, Elizabeth, Modjtahedi, Helmout and Carew, Mark A (2013) Resveratrol 3-O-d-glucuronide and resveratrol 4'-O-d-glucuronide inhibit colon cancer cell growth: Evidence for a role of A3 adenosine receptors, cyclin D1 depletion, and G1 cell cycle arrest. Molecular Nutrition and Food Research, 57(10), pp. 1708-1717. ISSN (print) 1613-4125

Brawn, Peter, Tyrrell, Elizabeth, Carew, Mark, Tesfa, Kibur Hunie and Greenwood, Iain (2012) A highly diastereoselective series of Nicholas cyclisation reactions of N-Boc-protected propargylamines. Tetrahedron, 68(48), pp. 10040-10048. ISSN (print) 0040-4020

Young, John, Matharu, Rajinder, Carew, Mark and Fry, Christopher (2012) Inhibition of stretching-evoked ATP release from bladder mucosa by anticholinergic agents. BJU International, 110(8b), E397-E401. ISSN (print) 1464-4096

Waheed, Abdul, Barker, James, Barton, Stephen J, Owen, Caroline P, Ahmed, Sabbir and Carew, Mark A (2012) A novel steroidal saponin glycoside from Fagonia indica induces cell-selective apoptosis or necrosis in cancer cells. European Journal of Pharmaceutical Sciences, 47(2), pp. 464-473. ISSN (print) 0928-0987

Waheed, Abdul, Barker, James, Barton, Stephen J., Khan, Gul-Majid, Najm-Us-Saqib, Qazi, Hussain, Manzoor, Ahmed, Sabbir, Owen, Caroline and Carew, Mark A. (2011) Novel acylated steroidal glycosides from Caralluma tuberculata induce caspase-dependent apoptosis in cancer cells. Journal of Ethnopharmacology, 137(3), pp. 1189-1196. ISSN (print) 0378-8741

Tyrrell, Elizabeth, Brawn, Peter, Carew, Mark and Greenwood, Iain (2011) An expedient conversion of [alpha]-amino acids into Weinreb amides using COMU (R) as a coupling agent. Tetrahedron Letters, 52(3), pp. 369-372. ISSN (print) 0040-4039

Ganbold, Munkhchimeg, Barker, James, Ma, Ren, Jones, Lucy and Carew, Mark (2010) Cytotoxicity and bioavailability studies on a decoction of Oldenlandia diffusa and its fractions separated by HPLC. Journal of Ethnopharmacology, 131(2), pp. 396-403. ISSN (print) 0378-8741

Pedrosa Ribeiro, Carla M., Paradiso, Anthony M., Carew, Mark, Shears, Stephen B. and Boucher, Richard C. (2005) Cystic fibrosis airway epithelial Ca2+ i signaling: the mechanism for the larger agonist-mediated Ca2+ i signals in human cystic fibrosis airway epithelia. Journal of Biological Chemistry, 280(11), pp. 10202-10209. ISSN (print) 0021-9258

Book

Carew, Mark (2018) The Book of Alexander. Norfolk, U.K. : Salt Publishing Limited. 240p. ISBN 9781784631321

Conference or Workshop Item

Waheed, Abdul, Barton, Stephen, Carew, Mark and Barker, James (2010) Isolation and structure elucidation of novel acylated pregnane glycosides from Caralluma tuberculata against human breast cancer cells MCF-7 cells. In: Structure 2010: Advances in structure elucidation; 24 - 25 Feb 2010, Leicester U.K..

Waheed, A., Barker, J., Barton, S. and Carew, M. (2009) In vitro evaluation of anti-proliferative activity of human breast cancer MCF-7 cells from ethno-pharmacological healing plants. In: St George's Research Day, University of London; 2 Dec 2009, London, UK. (Unpublished)

This list was generated on Sun Aug 18 04:39:50 2019 BST.
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