Miss Caroline Soliman

Research project: Design of glucose sensitive polymeric matrices for delivery of antidiabetic drugs

Abstract

Diabetes mellitus is the most common endocrine disorder ofcarbohydrate metabolism. Despite there is no cure for diabetesmellitus, tight glycemic control is a contentious issue with anincreased incidence of hyperglycemia and possible increase inmorbidity and mortality. The development of non-invasive glucosebiosensors has accompanied the evolution of monitoring andtreatment of diabetes mellitus, substantially improved glycemiccontrol and preventing the rise and progression of diabetesrelated complications. Glucose biosensors could simultaneouslymeasure glucose and release the required dose of antidiabeticdrug would enhance glucose regulation and better managementof diabetes by providing a reducing medication variability andoptimizing hypoglycemic protection. Microneedles "MNs" systemscould reach the dermis without reaching the pain points, holdgreat promise for continuous and real-time monitoring of diabetes.Simply, designing of polymeric biodegradable microneedles usingCAD design, followed by 3D printing of the designed structure.Loading the desired drug on the tip of the fabricated MNAs by aspin-casting method. Then, the prepared MNs will be subjected todifferent characterization techniques.

Biography

Caroline Fathy Lamie Soliman, an esteemed Assistant Lecturer of Pharmaceutics and Pharmaceutical Sciences at the British University in Egypt, has dedicated her career to the advancement of pharmaceutical knowledge and the pursuit of excellence in academia. With a passion for research and a commitment to making a difference in the field, Caroline has emerged as a prominent figure in the realm of pharmaceutical sciences. Her journey of scholarly achievement and impactful contributions has been marked by perseverance, dedication, and a relentless pursuit of excellence.Background and Education:Caroline's journey in the field of pharmacy began with her enrollment at the Faculty of Pharmacy, Cairo University. It was during her time there that she developed a strong foundation in pharmaceutical sciences, gaining a deep understanding of the intricacies of drug development and patient care. The rigorous curriculum and exposure to diverse research opportunities laid the groundwork for her future endeavors.Driven by a thirst for knowledge and a desire to explore her chosen field further, Caroline pursued her Master's degree in Pharmaceutics from Ain Shams University. This period of advanced study allowed her to delve into specialized areas of drug formulation, delivery systems, and pharmaceutical technology. Under the guidance of distinguished professors and mentors, she honed her research skills and acquired a comprehensive understanding of cutting-edge techniques and methodologies.Contributions and Research:Throughout her academic journey, Caroline's dedication and passion for research have been evident. As a result, she has made notable contributions to the field of pharmaceutical sciences. Caroline's research has focused on areas such as novel drug delivery systems, formulation development, and optimization of drug therapies. Her innovative approaches and insightful findings have been published in four esteemed scientific journals, cementing her reputation as a promising researcher.Teaching and Mentorship:In addition to her research endeavors, Caroline is deeply committed to nurturing the next generation of pharmaceutical scientists. As an Assistant Lecturer at the British University in Egypt, she imparts her knowledge and expertise to aspiring pharmacists. Her engaging teaching style, combined with her ability to simplify complex concepts, has earned her the respect and admiration of her students. Caroline also serves as a mentor, guiding and supporting young researchers, fostering their growth and empowering them to make their mark in the field.

Areas of research interest

  • Nanotechnology
  • Drug design
  • Glucose sensors
  • pharmacology

Qualifications

  • Bachelor degree in pharmaceutical science, Cairo university, Egypt
  • Master degree in pharmaceutics and pharmaceutical technology, Ain Shams University, Egypt

Funding or awards received

  • The first-place prize at the symposium of poster tittled " Aspasomal nanocarriers; unlocking the potential of repurposed itraconazole for skin cancer therapy- a promising anticancer cream"-Royal society of chemistry RSC, London, UK

Publications

  •  Diversifying the skin cancer-fighting worthwhile frontiers: How relevant are the itraconazole/ascorbyl palmitate nanovectors? 
  •  Assessment of antifungal efficacy of itraconazole loaded aspasomal cream: comparative clinical studyLinks to an external site.
  •  Management of recurrent aphthous ulcers exploiting polymer-based Muco-adhesive sponges: in-vitro and in-vivo evaluationLinks to an external site.
  •  Tackling acne vulgaris by fabrication of tazarotene-loaded essential oil-based microemulsion: In vitro and in vivo evaluationLinks to an external site.