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After studying Biophysics in St-Petersburg, Russia, I joined the European Molecular Biology Laboratory (Hamburg Outstation, Germany) for a PhD in Structural Biology. In 2006 I moved to Harvard Medical School (Boston, USA) as a postdoctoral fellow and in 2009 I was awarded a Human Frontier postdoctoral fellowship for a structural biology project to work at the Institute of Cancer Research (London, UK). 2014-2019 I have been working at University of Oxford, UK and combining research and teaching.
I have joined Kingston University in 2020. I teach on a range of Biochemistry, Biomedical Sciences and Biological Science courses.
My current research interests focus on the use of structural biology approaches to investigate mechanisms underlying disease (neurodegenerative and cardiovascular). In addition, I am interested in pedagogical development.
2019 Lamber E. P., Siedenburg A. C., Barr F. A. Rab regulation by GEFs and GAPs during membrane trafficking. Review. Current Opinion in Cell Biology 2019 Apr 10; 59:34-39
2015 Chaban Y., Stead J. A., Ryzhenkova K., Whelan F., Lamber E. P., Antson A., Sanders C. M., Orlova E. V. Structural basis of DNA strand separation by a hexameric replicative helicase. Nucleic Acids Res. 2015; Sep 30;43(17):8551-63
2013 Lamber E. P.*, Beuron F., Svergun D. I., Morris E., Mittnacht S*. Structural insights into the mechanism of phosphoregulation of the retinoblastoma protein. PLoS ONE. 2013; 8(3):e58463 (* corresponding authors)
2012 Bunney T. D., Esposito D., Mas-Droux C., Lamber E.P., Baxendale R. W., Martins M., Cole A., Svergun D. I., Driscoll P.D., M. Katan. Structural and functional integration of the PLCγ interaction domains critical for regulatory mechanisms and signaling deregulation. Structure. 2012 Dec 5; 20(12):2062-75.
2010 Lamber E. P., Horwitz A., Parvin J. BRCA1 represses Amphiregulin gene expression. Cancer Res. 2010 Feb 1; 70(3):996-1005
2008 Lamber E. P., Vanhille L., Textor L., Kachalova G. S., Sieweke M. H., Wilmanns M. Regulation of the transcription factor Ets-1 by DNA-mediated homo-dimerization. EMBO J. 2008 Jul 23; 27(14):2006-17
2008 Lamber E. P., Svergun D. I., Wilmanns M. Low resolution structural models of the b/HLH/Z domain of USF1 and its complexes with DNA from small angle X-ray scattering data. Biophys J. 2008 Jan 1; 94(1):193-7 [EG1]
2001 Mandel'shtam M. I., Golubkov V. I., Lamber E. P., Shapiro I. M., Lipovetsky B. M., Breshneva T. V., Semiglazov V. F., Xanson K. P., Gaitshoki V. S. Search for common mutations predisposing to breast cancer. Genetika. 2001 Dec; 37(12):1681-6