Dr Katya Lamber

About

After studying Biophysics in St-Petersburg, Russia, I joined the European Molecular Biology Laboratory (Hamburg Outstation, Germany) for a PhD in Structural Biology. In 2006 I moved to Harvard Medical School (Boston, USA) as a postdoctoral fellow and in 2009 I was awarded a Human Frontier postdoctoral fellowship for a structural biology project to work at the Institute of Cancer Research (London, UK). 2014-2019 I have been working at University of Oxford, UK and combining research and teaching. 

I have joined Kingston University in 2020. I teach on a range of Biochemistry, Biomedical Sciences and Biological Science courses. 

My current research interests focus on the use of structural biology approaches to investigate mechanisms underlying disease (neurodegenerative and cardiovascular) and to study bacterial pathogenesis. In addition, I am interested in pedagogical development.

Academic responsibilities

Lecturer in Biochemistry and Microbiology

Qualifications

  • M. Sc. in Biophysics (St-Petersburg, Russia)
  • PhD in Structural Biology (EMBL and Heidelberg University, Germany)
  • SEDA PDF Support Learning Award (UK)
  • Fellow of the Higher Education Academy (UK)

Teaching and learning

Courses taught:

  • Biochemistry BSc (Hons)
  • Biological Sciences BSc (Hons)
  • Biomedical Science BSc (Hons)
  • Science foundation year

Research

Publications:

 2019      Lamber E. P., Siedenburg A. C., Barr F. A. Rab regulation by GEFs and GAPs during membrane trafficking. Review. Current Opinion in Cell Biology 2019 Apr 10; 59:34-39

2015      Chaban Y., Stead J. A., Ryzhenkova K., Whelan F., Lamber E. P., Antson A., Sanders C. M., Orlova E. V. Structural basis of DNA strand separation by a hexameric replicative helicase.  Nucleic Acids Res. 2015; Sep 30;43(17):8551-63

2013      Lamber E. P.*, Beuron F., Svergun D. I., Morris E., Mittnacht S*. Structural insights into the mechanism of phosphoregulation of the retinoblastoma protein. PLoS ONE. 2013; 8(3):e58463 (* corresponding authors)

2012      Bunney T. D., Esposito D., Mas-Droux C., Lamber E.P., Baxendale R. W., Martins M., Cole A., Svergun D. I., Driscoll P.D., M. Katan. Structural and functional integration of the PLCγ interaction domains critical for regulatory mechanisms and signaling deregulation. Structure. 2012 Dec 5; 20(12):2062-75.

2010      Lamber E. P., Horwitz A., Parvin J. BRCA1 represses Amphiregulin gene expression. Cancer Res. 2010 Feb 1; 70(3):996-1005

2008      Lamber E. P., Vanhille L., Textor L., Kachalova G. S., Sieweke M. H., Wilmanns M. Regulation of the transcription factor Ets-1 by DNA-mediated homo-dimerization. EMBO J. 2008 Jul 23; 27(14):2006-17

2008      Lamber E. P., Svergun D. I., Wilmanns M. Low resolution structural models of the b/HLH/Z domain of USF1 and its complexes with DNA from small angle X-ray scattering data. Biophys J. 2008 Jan 1; 94(1):193-7  [EG1] 

2001      Mandel'shtam M. I., Golubkov V. I., Lamber E. P., Shapiro I. M., Lipovetsky B. M., Breshneva T. V., Semiglazov V. F., Xanson K. P., Gaitshoki V. S. Search for common mutations predisposing to breast cancer. Genetika. 2001 Dec; 37(12):1681-6

Research student supervision