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Dr Natasha Hill

Associate Professor

About

I graduated from Bristol University with a degree in Biochemistry before completing a PhD in the Genetics of Type 1 diabetes at Oxford under the supervision of Prof John Todd. I then moved to the USA to work with Dr Nora Sarvetnick at The Scripps Research Institute in La Jolla, investigating the regulation of autoimmunity by a particular gene variant in the non-obese diabetic (NOD) model of type 1 diabetes. I returned to the UK and worked briefly as an independent research fellow at the Blizard Institute (part of Barts and The London) before obtaining a permanent position at Kingston University in 2008. My current research is focused on finding novel approaches to promote islet regeneration, and my lab also has an interest in pancreatic cancer. I teach genetics and molecular biology at undergraduate level as well as contributing to teaching on the Cancer Biology MSc.

Areas of specialism

  • Diabetes
  • Islet regeneration
  • Autoimmunity
  • Pancreatic cancer
  • Matricellular proteins
  • Alternative splicing

Publications

Number of items: 15.

Article

Hill, Natasha, Denholm-Price, James, Atkins, Nigel, Tojal Dourado, Luis, Nimoh, Owuraku and Page, Nigel (2016) Does group assessment impact BME attainment? New Directions in the Teaching of Physics, 11(1), ISSN (online) 2051-3615

Viloria, Katrina and Hill, Natasha J. (2016) Embracing the complexity of matricellular proteins : the functional and clinical significance of splice variation. Biomolecular Concepts, 7(2), pp. 117-132. ISSN (print) 1868-5021

Viloria, Katrina, Munasinghe, Amanda, Asher, Sharan, Bogyere, Roberto, Jones, Lucy and Hill, Natasha (2016) A holistic approach to dissecting SPARC family protein complexity reveals FSTL-1 as an inhibitor of pancreatic cancer cell growth. Scientific Reports, 6, p. 37839. ISSN (online) 2045-2322

Ryall, Claire, Viloria, Katrina, Lhaf, Fadel, Walker, Tony, King, Aileen, Jones, Peter, Mackintosh, David, Mcniece, Rosemary, Kocher, Hemant, Flodstrom-Tullberg, Malin, Edling, Charlotte and Hill, Natasha (2014) Novel role for matricellular proteins in the regulation of islet [beta] cell survival: the effect of SPARC on survival, proliferation and signalling. The Journal of Biological Chemistry, 289, pp. 30614-30624. ISSN (print) 0021-9258

Yadav, Deepak, Hill, Natasha, Yagita, Hideo, Azuma, Miyuki and Sarvetnick, Nora (2009) Altered availability of PD-1/PD ligands is associated with the failure to control autoimmunity in NOD mice. Cellular Immunology, 258(2), pp. 161-171. ISSN (print) 0008-8749

McGuire, Helen M., Vogelzang, Alexis, Hill, Natasha, Flodstrom-Tullberg, Malin, Sprent, Jonathan and King, Cecile (2009) Loss of parity between IL-2 and IL-21 in the NOD Idd3 locus. Proceedings of the National Academy of Sciences, 106(46), pp. 19438-19443. ISSN (print) 0027-8424

Hultcrantz, M., Jacobson, S., Hill, N. J., Santamaria, P. and Flodström-Tullberg, M. (2009) The target cell response to cytokines governs the autoreactive T cell repertoire in the pancreas of NOD mice. Diabetologia, 52(2), pp. 299-305. ISSN (print) 0012-186X

Hill, Natasha J., King, Cecile and Flodstrom-Tullberg, Malin (2008) Recent acquisitions on the genetic basis of autoimmune disease. Frontiers in Bioscience, 13(13), pp. 4838-4851. ISSN (print) 1093-9946

Hill, NJ, Stotland, AB and Sarvetnick, NE (2007) Distinct regulation of autoreactive CD4 T cell expansion by interleukin-4 under conditions of lymphopenia. Journal of Leukocyte Biology, 81, pp. 757-765. ISSN (print) 0741-5400

Hill, Natasha J, Stotland, Aleksander, Solomon, Michelle, Secrest, Patrick, Getzoff, Elizabeth and Sarvetnick, Nora (2007) Resistance of the target islet tissue to autoimmune destruction contributes to genetic susceptibility in Type 1 diabetes. Biology Direct, 2, p. 5. ISSN (online) 1745-6150

Hill, Natasha J., Hultcranz, Monica, Sarvetnick, Nora and Flodstrom-Tullberg, Malin (2007) The target tissue in autoimmunity : an influential niche. European Journal of Immunology, ISSN (print) 0014-2980

Hill, Natasha J., Van Gunst, Kurt and Sarvetnick, Nora (2003) Th1 and Th2 pancreatic inflammation differentially affects homing of islet-reactive CD4 cells in nonobese diabetic mice. The Journal of Immunology, 170(4), pp. 1649-1658. ISSN (print) 0022-1767

Hill, Natasha and Sarvetnick, Nora (2002) Cytokines: promoters and dampeners of autoimmunity. Current Opinion in Immunology, 14(6), pp. 791-797. ISSN (print) 0952-7915

Hill, N J, Lyons, P A, Armitage, N, Todd, J A, Wicker, L S and Peterson, L B (2000) The NOD Idd5 locus controls insulitis and diabetes and overlaps the orthologous CTLA4/IDDM12 and NRAMP1 loci in humans. Diabetes, 49(10), pp. 1744-1747. ISSN (print) 0012-1797

Conference or Workshop Item

Lhaf, F, Taylor, H, Austin, ALF, King, A, Jones, P, Turner, M, Jones, L and Hill, N (2015) Modulation of growth factor receptor trafficking as a novel approach to promoting beta cell expansion. In: Diabetes UK Professional Conference 2015 : Diabetes: time to take control; 11 - 13 Mar 2015, London, U.K..

This list was generated on Sat Jul 22 04:54:28 2017 BST.
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