Dr Andreas Hoppe


I am Senior Lecturer in the areas of Computer Science and Games Development. My research interests are in teaching and learning technologies as well as in digital imaging for quantitative microscopy.

Academic responsibilities

Senior Lecturer


  • PhD
  • BSc(Hons)

Teaching and learning


My research is in the field of bio-imaging. This encompasses research in algorithms and techniques for the segmentation and tracking of live cell-imaging sequences as well as the computer aided analysis of spatio-temporal properties of individual cells and cell clusters. 

Research student supervision


Number of items: 50.


Davis, John Robert, Ainslie, Anna P., Williamson, John J., Ferreira, Ana, Torres-Sánchez, Alejandro, Hoppe, Andreas, Mangione, Federica, Smith, Matthew B., Martin-Blanco, Enrique, Salbreux, Guillaume and Tapon, Nicolas (2022) ECM degradation in the 'Drosophila' abdominal epidermis initiates tissue growth that ceases with rapid cell-cycle exit. Current Biology, 32(6), pp. 1285-1300. ISSN (print) 0960-9822

Tetley, Robert J., Staddon, Michael F., Heller, Davide, Hoppe, Andreas, Banerjee, Shiladitya and Mao, Yanlan (2019) Tissue fluidity promotes epithelial wound healing. Nature Physics, 15(11), pp. 1195-1203. ISSN (print) 1745-2473

Diaz-de-la-Loza, Maria-del-Carmen, Ray, Robert P., Ganguly, Poulami S., Alt, Silvanus, Davis, John R., Hoppe, Andreas, Tapon, Nic, Salbreux, Guillaume and Thompson, Barry J. (2018) Apical and basal matrix remodeling control epithelial morphogenesis. Developmental Cell, 46(1), 23-39.e5. ISSN (print) 1534-5807

Habib, Mohammed, Welikala, Roshan, Hoppe, Andreas, Owen, Christopher G., Rudnicka, Alicja R., Tufail, Adnan, Egan, Catherine and Barman, Sarah A. (2017) Incorporating spatial information for microaneurysm detection in retinal images. Advances in Science, Technology and Engineering Systems Journal, 2(3), pp. 642-649. ISSN (online) 2415-6698

Habib, M.M., Welikala, R.A., Hoppe, A., Owen, C.G., Rudnicka, A.R. and Barman, S.A. (2017) Detection of microaneurysms in retinal images using an ensemble classifier. Informatics in Medicine Unlocked, 9, pp. 44-57. ISSN (print) 2352-9148

Heller, Davide, Hoppe, Andreas, Restrepo, Simon, Gatti, Lorenzo, Tournier, Alexander L., Tapon, Nicolas, Basler, Konrad and Mao, Yanlan (2016) EpiTools : an open-source image analysis toolkit for quantifying epithelial growth dynamics. Developmental Cell, 36(1), pp. 103-116. ISSN (print) 1534-5807

Welikala, R.A., Fraz, M.M., Dehmeshki, J., Hoppe, A., Tah, V., Mann, S., Williamson, T.H. and Barman, S.A. (2015) Genetic algorithm based feature selection combined with dual classification for the automated detection of proliferative diabetic retinopathy. Computerized Medical Imaging and Graphics, 43, pp. 64-77. ISSN (print) 0895-6111

Welikala, R.A., Dehmeshki, J., Hoppe, A., Tah, V., Mann, S., Williamson, T.H. and Barman, S. A. (2014) Automated detection of proliferative diabetic retinopathy using a modified line operator and dual classification. Computer Methods and Programs in Biomedicine, 114(3), pp. 247-261. ISSN (print) 0169-2607

Reljic, Rajko, Sibley, Laura, Huang, Jen-Min, Pepponi, Ilaria, Hoppe, Andreas, Hong, Huynh A. and Cutting, Simon M. (2013) Mucosal Vaccination against Tuberculosis Using Inert Bioparticles. Infection And Immunity, 81(11), pp. 4071-4080. ISSN (print) 0019-9567

Willenbrock, Frances, Zicha, Daniel, Hoppe, Andreas and Hogg, Nancy (2013) Novel automated tracking analysis of particles subjected to shear flow: kindlin-3 role in B cells. Biophysical Journal, 105(5), pp. 1110-1122. ISSN (print) 0006-3495

Fraz, M. M., Remagnino, P., Hoppe, A., Rudnicka, A. R., Whincup, P.H., Owen, C. G. and Barman, S.A. (2013) Quantification of blood vessel calibre in retinal images of multi-ethnic school children using a model based approach. Computerized Medical Imaging and Graphics, 37(1), pp. 48-60. ISSN (print) 1879-0771

Mao, Y., Tournier, A.L., Hoppe, A., Kester, L., Thompson, B.J. and Tapon, N. (2013) Differential proliferation rates generate patterns of mechanical tension that orient tissue growth. The EMBO Journal, 32(21), pp. 2790-2803. ISSN (print) 0261-4189

Fraz, M. M., Barman, S. A., Remagnino, P., Hoppe, A., Basit, A., Uyyanonvara, B., Rudnicka, A. R. and Owen, C. G. (2012) An approach to localize the retinal blood vessels using bit planes and centerline detection. Computer Methods and Programs in Biomedicine, 108(2), pp. 600-616. ISSN (print) 0169-2607

Fraz, M.M., Remagnino, P., Hoppe, A., Uyyanonvara, B., Rudnicka, A.R., Owen, C.G. and Barman, S.A. (2012) Blood vessel segmentation methodologies in retinal images: a survey. Computer Methods and Programs in Biomedicine, 108(1), pp. 407-433. ISSN (print) 0169-2607

Fraz, M.M., Remagnino, P., Hoppe, A., Uyyanonvara, B., Rudnicka, A.R., Owen, C.G. and Barman, S.A. (2012) An ensemble classification based approach applied to retinal blood vessel segmentation. IEEE Transactions on Biomedical Engineering, 59(9), pp. 2538-2548. ISSN (print) 0018-9294

James, Joanna L., Cartwright, Judith E., Whitley, Guy S., Greenhill, Darrel R. and Hoppe, Andreas (2012) The regulation of trophoblast migration across endothelial cells by low shear stress: consequences for vascular remodelling in pregnancy. Cardiovascular Research, 93(1), pp. 152-161. ISSN (print) 0008-6363

Bakas, Spyridon, Chatzimichail, Katerina, Hoppe, Andreas, Galariotis, Vasileios, Hunter, Gordon and Makris, Dimitrios (2012) Histogram-based motion segmentation and characterisation of focal liver lesions in CEUS. Annals of the BMVA, 2012(7), pp. 1-14.

John, B., Khaddaj, S. and Hoppe, A. (2011) Performance assessment of semantic information search and linkage engine using ontology. International Journal of Computing Technology and Information Security, 1(1), pp. 24-29. ISSN (print) 2231-1998

John, Biju, Khaddaj, Souheil and Hoppe, Andreas (2010) Software metrics for the evaluation of semantic web applications. Journal of Algorithms and Computational Technology, 4(4), pp. 511-522. ISSN (print) 1748-3018

Hagglund, Samuel, Hoppe, Andreas, Aubyn, Deborah, Cavanna, Tamara, Jordan, Peter and Zicha, Daniel (2009) Novel shear flow assay provides evidence for non-linear modulation of cancer invasion. Frontiers in Bioscience, 14, pp. 3085-3093. ISSN (print) 1093-9946

Hamzic, E., Cartwright, J.E., Keogh, R.J., Whitley, G. St. J., Greenhill, D. and Hoppe, A. (2008) Live cell image analysis of cell-cell interactions reveals the specific targeting of vascular smooth muscle cells by fetal trophoblasts. Experimental Cell Research, 314(7), pp. 1455-1464. ISSN (print) 0014-4827

Korzynska, Anna, Strojny, Wojciech, Hoppe, Andreas, Wertheim, David and Hoser, Pawel (2007) Segmentation of microscope images of living cells. Pattern Analysis & Applications, 10(4), pp. 301-319. ISSN (print) 1433-7541

Oduncu, Hakan, Hoppe, Andreas, Clark, Michael, Williams, Robert J. and Harding, Keith G. (2004) Analysis of skin wound images using digital colour image processing: A preliminary communication. The International Journal of Lower Extremity Wounds, 3(3), pp. 151-156. ISSN (print) 1534-7346

Baradez, M-O., McGuckin, C.P., Forraz, N., Pettengell, R. and Hoppe, A. (2004) Robust and automated unimodal histogram thresholding and potential applications. Pattern Recognition, 37(6), pp. 1131-1148. ISSN (print) 0031-3203

Hoppe, A., Wertheim, D., Jiang, W.G., Williams, R. and Harding, K. (1999) Interactive image processing system for assessment of cell movement. Medical & Biological Engineering & Computing, 37(1), pp. 419-423. ISSN (print) 0140-0118

Hoppe, A., Jiang, W.G., Wertheim, D., Williams, R.J. and Harding, K.G. (1998) A system for computer analysis of cancer cell movement. Anticancer Research, 18(4A), pp. 2691-2694. ISSN (print) 0250-7005


Dehmeshki, Jamshid , Hoppe, Andreas and Greenhill, Darrel, eds. (2009) Proceedings of the Thirteenth Annual Conference: Medical Image Understanding and Analysis. BMVA. 265p. ISBN 1901725391

Hoppe, Andreas , Barman, Sarah and Ellis, Tim, eds. (2005) Proceedings of the British Machine Vision Conference 2004. Malvern, U.K. : British Machine Vision Association. ISBN 9781901725254

Book Section

Fraz, M.M., Remagnino, P., Hoppe, A., Uyyanonvara, B., Rudnicka, A.R., Owen, C.G. and Barman, S.A. (2012) Ensemble classification system applied for retinal vessel segmentation on child images containing various vessel profiles. In: Campilho, Aurélio and Kamel, Mohamed, (eds.) Image Analysis and Recognition. Berlin : Springer. pp. 380-389. (Lecture Notes in Computer Science, (7325)) ISSN (print) 0302-9743 ISBN 9783642312977

Fraz, M.M., Remagnino, P., Hoppe, A., Uyyanonvara, B., Owen, Christopher G, Rudnicka, Alicja R and Barman, S. (2011) Retinal Vessel Extraction Using First-Order Derivative of Gaussian and Morphological Processing. In: Bebis, George , Boyle, Richard , Parvin, Bahram , Koracin, Darko , Wang, Song , Kyungnam, Kim , Benes, Bedrich , Moreland, Kenneth , Borst, Christoph , DiVerdi, Stephen , Yi-Jen, Chiang and Ming, Jiang, (eds.) Advances in Visual Computing. Springer Berlin Heidelberg. pp. 410-420. (Lecture Notes in Computer Science, (6938)) ISSN (print) 0302-9743 ISBN 9783642240270

Conference or Workshop Item

Habib, M.M., Welikala, R.A., Hoppe, A., Owen, C.G., Rudnicka, A.R. and Barman, S.A. (2016) Microaneurysm detection in retinal images using an ensemble classifier. In: 6th International Conference of Image Processing Theory Tools and Applications (IPTA); 12 - 15 Dec 2016, Oulu, Finland. ISSN (online) 2154-512X ISBN 9781467389105

Welikala, Roshan A., Tah, Vikas, Williamson, Tom H., Hoppe, Andreas, Dehmeshki, Jamishid and Barman, Sarah (2014) Differing matched filter responsivity for the detection of proliferative diabetic retinopathy. In: Computer Graphics and Imaging / 798: Signal Processing, Pattern Recognition and Applications (CGIM 2013); 12-14 Feb 2013, Innsbruck, Austria. ISSN (print) 0146-664X

Mclay, Tony, Hoppe, Andreas, Greenhill, Darrel R. and Khaddaj, Souheil (2013) The DFrame: Parallel programming using a distributed framework implemented in MPI. In: 12th International Symposium on Distributed Computing and Applications to Business, Engineering & Science; 2-4 Sept. 2013, Los Alamitos, CA, U.S.A.. ISBN 9780769550602

Fraz, M.M., Remagnino, P., Hoppe, A. and Barman, S. (2013) Retinal image analysis aimed at extraction of vascular structure using linear discriminant classifier. In: IEEE International Conference on Computer Medical Applications (ICCMA); 20-22 Jan. 2013, Sousse, Tunisia. ISBN 9781467352130

Fraz, M.M., Remagnino, P., Hoppe, A., Barman, S.A., Rudnicka, A., Owen, C. and Whincup, P. (2012) A Model Based Approach for Vessel Caliber Measurement in Retinal Images. In: Eighth International Conference on Signal Image Technology and Internet Based Systems (SITIS); 25-29 Nov 2012, Sorrento, Italy. ISBN 9781467351522

Bakas, S., Hoppe, A., Chatzimichail, K, Galariotis, V, Hunter, G. and Makris, D. (2012) Focal liver lesion tracking in CEUS for characterisation based on dynamic behaviour. In: 8th International Symposium on Visual Computing (ISVC); 16-18 July 2012, Rethymnon, Crete, Greece.

Fraz, M. M., Remagnino, P., Hoppe, A., Uyyanonvara, B., Rudnicka, A., Owen, C. G. and Barman, S. A. (2012) Retinal vessel segmentation using ensemble classifier of bagged decision trees. In: IET Conference on Image Processing (IPR 2012); 03 - 04 Jul 2012, London, U.K..

Fraz, Muhammad Moazam, Remagnino, Paolo, Hoppe, Andreas, Velastin, Sergio A. and Barman, Sarah (2011) A supervised method for retinal blood vessel segmentation using line strength multiscale gabor and morphological features. In: IEEE International Conference on Signal and Image Processing Applications; 16 - 18 Nov 2011, Kuala Lumpur, Malaysia. ISBN 9781457702433

Fraz, M. Moazam, Basit, Abdul, Remagnino, Paolo, Hoppe, Andreas and Barman, Sarah (2011) Retinal vasculature segmentation by morphological curvature, reconstruction and adapted hysteresis thresholding. In: IEEE International Conference on Emerging Technologies; 05 - 06 Sep 2011, Islamabad, Pakistan. ISBN 9781457707698

Bakas, Spyridon, Chatzimichail, Katerina, Autret, Awen, Hoppe, Andreas, Galariotis, Vasileios and Makris, Dimitrios (2011) Localisation and characterisation of focal liver lesions using contrast-enhanced ultrasonographic visual cues. In: Medical Image Understanding and Analysis; 14-15 July 2011, London, U.K..

Zicha, D. and Hoppe, A. (2011) Developing imaging-based invasion assays. In: 11th International ELMI Meeting on Advanced Light Microscopy; 7-10 Jun 2010, Alexandroupolis, Greece. (Unpublished)

Zicha, Daniel, Hoppe, Andreas, Aubyn, Deborah and Jordan, Peter (2009) Invasion of metastatic cells into monolayers of endothelial cells analysed directly with shear flow in vitro. In: NCRI Cancer Conference; 4 - 7 Oct 2009, Birmingham, U.K..

John, B., Khaddaj, Souheil and Hoppe, A. (2009) Accelerating user satisfaction in semantic e-commerce. In: Second International Conference on the Applications of Digital Information and Web Technologies; 04 - 06 Aug 2009, London, U.K.. ISBN 9781424444564

Khaddaj, S. and Hoppe, Andreas (2009) An object model for the management of digital images. In: 11th International Conference on Enterprise Information Systems; 6 May - 10 May 2009, Milan, Italy.

McLay, Tony, Hoppe, Andreas, Greenhill, Darrel R. and Khaddaj, Souheil (2009) A distributed imaging framework to extract, analyse and visualize cell features in multi-dimensional bio-image datasets. In: International Symposium on Distributed Computing and Applications to Business, Engineering and Science; 16 - 19 Oct 2009, Wuhan,Hubei, China.

Baradez, M-O. and Hoppe, A. (2003) Thresholding based on linear diffusion for feature segmentation. In: British Machine Vision Conference; 8 Sept - 11 Sept 2003, Norwich, U.K.. ISBN 1901725243

Hoppe, A., Wertheim, D., Melhuish, J., Morris, H., Harding, K.G. and Williams, R. (2001) Computer assisted assessment of wound appearance using digital imaging. In: 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society; 25 Oct - 28 Oct 2001, Istanbul, Turkey. ISSN (print) 1094-687X ISBN 0780372115

Hoppe, A., Wertheim, D., Melhuish, J., Harding, K.G. and Williams, R.J. (2000) A spline based method for assessment of wound images. In: 1st International Conference on Advances in Medical Signal and Information Processing; 4-6 Sep 2000, Bristol, UK. (IEE Conference Publications, no. 476) ISSN (print) 0537-9989 ISBN 0852967284

Hoppe, A., Hallett, M.B., Dewitt, S. and Wertheim, D. (2000) Adaptive spline method for extracting Ca2+ and morphological measurements from motile human neutrophils. In: Medical Image Understanding and Analysis, 4th annual conference; Jul 2000, London, UK. ISBN 1901725111

Hoppe, A., Korzynska, A. and Wertheim, D. (1999) A computer system for the analysis of neutrophil movement. In: EMBEC '99 - European Medical & Biological Engineering Conference; 04 - 07 Nov 1999, Vienna, Austria.

This list was generated on Sat Apr 13 07:04:08 2024 BST.