Dr Francesca Mackenzie
Lecturer in Physiology and Pharmacology
Contact
- Email: f.mackenzie@kingston.ac.uk
- Location: Penrhyn Road
- Faculty: Faculty of Science, Engineering and Computing
- School: School of Life Sciences, Pharmacy and Chemistry
- Department: Department of Chemical and Pharmaceutical Sciences
About
I obtained my PhD from University of Oxford and MRC Harwell Mammalian Genetics Uni in 2001, where I worked on the genetics and pathophysiology of deafness. I then researched neuromuscular biology at MRC Harwell and neuronal development, regeneration and degeneration at UCL Institute of Ophthalmology during my postdoctoral work.
I joined Kingston University in 2017 as Lecturer in Physiology and Pharmacology with a specialism in neuroscience.
My research interests are in neuronal development and regeneration, particularly in the peripheral nervous system and in the eye.
Areas of specialism
- Neurobiology
- Physiology
- Pharmacology
- Genetics
- Developmental biology
Courses taught
Undergraduate
Qualifications
- 2018 Fellow of the Higher Education Academy (FHEA)
- 2017 Associate Fellow of the Higher Education Academy (AFHEA)
- 2006 DPhil (Oxon) Genetics, University of Oxford
- 2001 BSc (Hons) Applied Biology, University of Bath
Professional membership
Fellow of the Higher Education Academy (FHEA)
Genetics Society, Ambassador
British Society for Developmental Biology, Member
British Neuroscience Association, Member
UK Cell Adhesion Society, Member
Research
My research interests are in neuronal development and regeneration, particularly in the peripheral nervous system and in the eye.
Lab members:
Almas Mahmood (MScR student)
Agne Mikailionyte (PhD student)
Relevant publications
Cattin AL, Burden JJ, Van Emmenis L, Mackenzie FE et al. Macrophage-Induced Blood Vessels Guide Schwann Cell-Mediated Regeneration of Peripheral Nerves. Cell (2015).
Wiszniak S, Mackenzie FE, Anderson P, Kabbara S, Ruhrberg C, Schwarz Q. Neural crest cell-derived VEGF promotes embryonic jaw extension. PNAS (2015).
Mackenzie FE. & Ruhrberg, C. Diverse roles of VEGF-A in the nervous system. Development (2012).
Tillo M, Ruhrberg C, & Mackenzie, F. Emerging roles for semaphorins and VEGFs in synaptogenesis and synaptic plasticity. Cell Adhesion and Migration (2012).
Mackenzie FE, et al. Upregulation of PKD1L2 provokes a complex neuromuscular disease in the mouse. Hum Mol Genet (2009)
Research student supervision
Publications
Jump to: Article
Number of items: 3.
Article
Athanasiou, Dimitra, Aguila, Monica, Opefi, Chikwado A., South, Kieron, Bellingham, James, Bevilacqua, Dalila, Munro, Peter M., Kanuga, Naheed, Mackenzie, Francesca E., Dubis, Adam M., Georgiadis, Anastasios, Graca, Anna B., Pearson, Rachael A., Ali, Robin R., Sakami, Sanae, Palczewski, Krysztof, Sherman, Michael Y., Reeves, Philip J. and Cheetham, Michael E. (2017) Rescue of mutant rhodopsin traffic by metformin-induced AMPK activation accelerates photoreceptor degeneration. Human Molecular Genetics, 26(2), pp. 305-319. ISSN (print) 0964-6906
Cattin, Anne-Laure, Burden, Jemima J., Van Emmenis, Lucie, Mackenzie, Francesca E., Hoving, Julian J.A., Garcia Calavia, Noelia, Guo, Yanping, McLaughlin, Maeve, Rosenberg, Laura H., Quereda, Victor, Jamecna, Denisa, Napoli, Ilaria, Parrinello, Simona, Enver, Tariq, Ruhrberg, Christiana and Lloyd, Alison C. (2015) Macrophage-induced blood vessels guide Schwann cell-mediated regeneration of peripheral nerves. Cell, 162(5), pp. 1127-1139. ISSN (print) 0092-8674
Wiszniak, S, Mackenzie, FF, Anderson, P, Kabbara, S, Ruhrberg, C and Schwarz, Q (2015) Neural crest cell-derived VEGF promotes embryonic jaw extension. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 112(19), pp. 6086-6091. ISSN (online) 0027-8424