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Dr Francesca Mackenzie

About

I obtained my PhD from University of Oxford and MRC Harwell Mammalian Genetics Unit in 2001, where I worked on the genetics and pathophysiology of deafness. I then researched neuromuscular biology at MRC Harwell, and neuronal development, regeneration and degeneration at UCL Institute of Ophthalmology, during postdoctoral work.

I joined Kingston University in 2017 as Lecturer in Physiology and Pharmacology with a specialism in neuroscience.

My research interests are in neuronal development and regeneration, particularly in the peripheral nervous system and in the eye.

Academic responsibilities

Senior Lecturer in Physiology and Pharmacology

Qualifications

  • 2018 Fellow of the Higher Education Academy (FHEA)
  • 2017 Associate Fellow of the Higher Education Academy (AFHEA)
  • 2006 DPhil (Oxon) Genetics, University of Oxford
  • 2001 BSc (Hons) Applied Biology, University of Bath

Teaching and learning

Research

My research interests are in neuronal development and regeneration, particularly in the peripheral nervous system and in the eye.

Current lab members:

  • Almas Mahmood (MScR)
  • Lucrezia Bruno (PhD)
  • Agne Mikailionyte (PhD)
  • Amtul Bhunnoo (PhD, 2nd supervisor)
  • Elizabeth Spiritosanto (MScR, 2nd supervisor)
  • Kelly Wong (PhD, 2nd supervisor)

Relevant publications

Cattin AL, Burden JJ, Van Emmenis L, Mackenzie FE et al. Macrophage-Induced Blood Vessels Guide Schwann Cell-Mediated Regeneration of Peripheral Nerves. Cell (2015).

Wiszniak S, Mackenzie FE, Anderson P, Kabbara S, Ruhrberg C, Schwarz Q. Neural crest cell-derived VEGF promotes embryonic jaw extension. PNAS (2015).

Mackenzie FE. & Ruhrberg, C. Diverse roles of VEGF-A in the nervous system. Development (2012).

Tillo M, Ruhrberg C, & Mackenzie, F. Emerging roles for semaphorins and VEGFs in synaptogenesis and synaptic plasticity. Cell Adhesion and Migration (2012).

Mackenzie FE, et al. Upregulation of PKD1L2 provokes a complex neuromuscular disease in the mouse. Hum Mol Genet (2009)

Research student supervision

Publications

Jump to: Article
Number of items: 3.

Article

Athanasiou, Dimitra, Aguila, Monica, Opefi, Chikwado A., South, Kieron, Bellingham, James, Bevilacqua, Dalila, Munro, Peter M., Kanuga, Naheed, Mackenzie, Francesca E., Dubis, Adam M., Georgiadis, Anastasios, Graca, Anna B., Pearson, Rachael A., Ali, Robin R., Sakami, Sanae, Palczewski, Krysztof, Sherman, Michael Y., Reeves, Philip J. and Cheetham, Michael E. (2017) Rescue of mutant rhodopsin traffic by metformin-induced AMPK activation accelerates photoreceptor degeneration. Human Molecular Genetics, 26(2), pp. 305-319. ISSN (print) 0964-6906

Cattin, Anne-Laure, Burden, Jemima J., Van Emmenis, Lucie, Mackenzie, Francesca E., Hoving, Julian J.A., Garcia Calavia, Noelia, Guo, Yanping, McLaughlin, Maeve, Rosenberg, Laura H., Quereda, Victor, Jamecna, Denisa, Napoli, Ilaria, Parrinello, Simona, Enver, Tariq, Ruhrberg, Christiana and Lloyd, Alison C. (2015) Macrophage-induced blood vessels guide Schwann cell-mediated regeneration of peripheral nerves. Cell, 162(5), pp. 1127-1139. ISSN (print) 0092-8674

Wiszniak, S, Mackenzie, FF, Anderson, P, Kabbara, S, Ruhrberg, C and Schwarz, Q (2015) Neural crest cell-derived VEGF promotes embryonic jaw extension. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 112(19), pp. 6086-6091. ISSN (online) 0027-8424

This list was generated on Wed Jan 22 05:30:37 2020 GMT.
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