Lactate monitoring using fluorescence with stable boronic acid-functionalized nanoparticles from Polymerization-Induced Self-Assembly (PISA)
Balouchi, Morvarid, Liu, Zixiao, Ishizuka, Fumi, Bear, Joseph, Kadri, Hachemi, Zetterlund, Per B. and Aldabbagh, Fawaz, 2026, Langmuir (42), 20 pp 14281-14289, Published
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From solid dispersions to enzyme-responsive nanocarriers: whey protein isolate nanoparticles for enhanced curcumin encapsulation and targeted delivery
Megahed, Marwa, Patel, Jaina, Najlah, Mohammad, Kadri, Hachemi and Khoder, Mouhamad, 2026, Pharmaceutics (18), 5, Published
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Targeting kinetoplastid parasites with ProTide prodrugs: a proof‐of‐concept study
Lowe, Silvester, Satikuvar, Vishal, Syeda, Tanjia M., Cal, Monica, Mäser, Pascal, Kaiser, Marcel and Kadri, Hachemi, 2026, ChemMedChem (21), 7, Published
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Albumin nanoparticles in cancer therapeutics: clinical Status, challenges, and future directions
Kadri, Hachemi, Alshatfa, Mesk, Alsalloum, Feras Z., Elhissi, Abdelbary, Daou, Anis and Khoder, Mouhamad, 2025, Pharmaceutics (17) pp 1290, Published
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Nucleoside analogues for chagas disease and leishmaniasis therapy: current status and future perspectives
Nwoke, Emmanuel Awucha, Lowe, Silvester, Aldabbagh, Fawaz, Kalesh, Karunakaran and Kadri, Hachemi, 2024, Molecules (29), 22, Published
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Aryloxy diester phosphonamidate prodrugs of phosphoantigens (ProPAgens) as potent activators of V╬│9/V╬┤2 T-cell immune responses
Kadri, Hachemi, Taher, Taher E., Xu, Qin, Sharif, Maria, Ashby, Elizabeth, Bryan, Richard T., Willcox, Benjamin E. and Mehellou, Youcef, 2020, Journal of Medicinal Chemistry (63), 19 pp 11258-11270, Published
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Aryloxy triester phosphoramidates as phosphoserine prodrugs: a proof of concept study
Miccoli, Ageo, Dhiani, Binar A., Thornton, Peter J., Lambourne, Olivia A., James, Edward, Kadri, Hachemi and Mehellou, Youcef, 2020, ChemMedChem (15), 8 pp 671-674, Published
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The photosensitising clinical agent verteporfin is an inhibitor of SPAK and OSR1 kinases
AlAmri, Mubarak A., Kadri, Hachemi, Alderwick, Luke J., Jeeves, Mark and Mehellou, Youcef, 2018, ChemBioChem (19), 19 pp 2072-2080, Published
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C-terminal phosphorylation of SPAK and OSR1 kinases promotes their binding and activation by the scaffolding protein MO25
Mehellou, Youcef, Alamri, Mubarak A., Dhiani, Binar A. and Kadri, Hachemi, 2018, Biochemical and Biophysical Research Communications (503), 3 pp 1868-1873, Published
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Niclosamide: a drug with many (re)purposes
Kadri, Hachemi, Lambourne, Olivia A. and Mehellou, Youcef, 2018, ChemMedChem (13), 11 pp 1088-1091, Published
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The anthelmintic drug niclosamide and its analogues activate the Parkinson's disease associated protein kinase PINK1
Barini, Erica, Miccoli, Ageo, Tinarelli, Federico, Mulholland, Katie, Kadri, Hachemi, Khanim, Farhat, Stojanovski, Laste, Read, Kevin D., Burness, Kerry, Blow, Julian J., Mehellou, Youcef and Muqit, Miratul M.K., 2018, ChemBioChem (19), 5 pp 425-429, Published
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BTN3A1 discriminates ╬│╬┤ T cell phosphoantigens from nonantigenic small molecules via a conformational sensor in its B30.2 domain
Salim, Mahboob, Knowles, Timothy J., Baker, Alfie T., Davey, Martin S., Jeeves, Mark, Sridhar, Pooja, Wilkie, John, Willcox, Carrie R., Kadri, Hachemi, Taher, Taher E., Vantourout, Pierre, Hayday, Adrian, Mehellou, Youcef, Mohammed, Fiyaz and Willcox, Benjamin E., 2017, ACS Chemical Biology (12), 10 pp 2631-2643, Published
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WNK signaling inhibitors as potential antihypertensive drugs
AlAmri, Mubarak A., Kadri, Hachemi, Dhiani, Binar A., Mahmood, Shumail, Elzwawi, Abdulrahman and Mehellou, Youcef, 2017, ChemMedChem (12), 20 pp 1677-1686, Published
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Rafoxanide and closantel inhibit SPAK and OSR1 kinases by binding to a highly conserved allosteric site on their C-terminal domains
AlAmri, Mubarak A., Kadri, Hachemi, Alderwick, Luke J., Simpkins, Nigel S. and Mehellou, Youcef, 2017, ChemMedChem (12), 9 pp 639-645, Published
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Kinetin riboside and its ProTides activate the Parkinson's disease associated PTEN-induced putative kinase 1 (PINK1) independent of mitochondrial depolarization
Osgerby, Laura, Lai, Yu Chiang, Thornton, Peter J., Amalfitano, Joseph, Le Duff, Cécile S., Jabeen, Iqra, Kadri, Hachemi, Miccoli, Ageo, Tucker, James H.R., Muqit, Miratul M.K. and Mehellou, Youcef, 2017, Journal of Medicinal Chemistry (60), 8 pp 3518-3524, Published
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Towards the development of small-molecule MO25 binders as potential indirect SPAK/OSR1 kinase inhibitors
Kadri, Hachemi, Alamri, Mubarak A., Navratilova, Iva H., Alderwick, Luke J., Simpkins, Nigel S. and Mehellou, Youcef, 2017, ChemBioChem (18), 5 pp 460-465, Published
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Nucleoside phosphate and phosphonate prodrug clinical candidates
Thornton, Peter J., Kadri, Hachemi, Miccoli, Ageo and Mehellou, Youcef, 2016, Journal of Medicinal Chemistry (59), 23 pp 10400-10410, Published
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Synthesis and antioxidant properties of substituted
2-phenyl-1H-indoles
Karaaslan, Cigdem, Kadri, Hachemi, Coban, Tulay, Suzen, Sibel and Westwell, Andrew D., 2013, Physikalische Medizin Rehabilitationsmedizin Kurortmedizin (23), 9 pp 2671-2674, Published
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The design, synthesis and antitumour evaluation of novel small
molecule inhibitors of the Dishevelled PDZ domain
Kadri, H., Dale, T.C., Ewan, K.B.R. and Westwell, A.D., 2008, European Journal of Cancer Supplements (6), 12, Published
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Synthesis and biological properties of benzothiazole, benzoxazole, and chromen-4-one analogues of the potent antitumor agent 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (PMX 610, NSC 721648)
Aiello, Stefania, Wells, Geoffrey, Stone, Erica L., Kadri, Hachemi, Bazzi, Rana, Bell, David R., Stevens, Malcolm F.G., Matthews, Charles S., Bradshaw, Tracey D. and Westwell, Andrew D., 2008, Journal of Medicinal Chemistry (51), 16 pp 5135-5139, Published
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The development of pro-apoptotic cancer therapeutics
Ziedan, Noha I., Kadri, Hachemi and Westwell, Andrew D., 2008, Mini-Reviews in Medicinal Chemistry (8), 7 pp 711-718, Published
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Synthesis and antitumour evaluation of novel 2-
phenylbenzimidazoles
Kadri, Hachemi, Matthews, Charles S., Bradshaw, Tracey D., Stevens, Malcolm F.G. and Westwell, Andrew D., 2008, Journal of Enzyme Inhibition and Medicinal Chemistry (23), 5 pp 641-647, Published
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