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I am a chemist who has gained industrial expertise in the research and development of bioconjugate synthesis and purification, ranging from labelling of antibodies with UV active/fluorescent probes, drugs, dendrimers/macromolecules/polymers, latex and polystyrene beads or other proteins to immunogen synthesis. This in combination with my background in organic/material chemistry led to an interest in the synthesis or modification of small molecules, e.g. drugs for antibody drug conjugates (ADC), UV active labels for detection and larger molecules, e.g. dendrimers, amino-dextran for either carrier or scaffold structures attached to antibodies for use in the pharmaceutical industry.
My interest in this novel area of research combined with my industrial knowledge of working to industrial sector quality standards i.e. ISO9001/13485 accredited laboratories, has provided me with the platform to embed these vital skills needed to the next generation of scientists.
Lecturer in Pharmaceutical Science
After obtaining my PhD in organic/materials chemistry, titled "The Synthesis and Properties of Phenyl-Cored Thiophene Dendrimers" I quickly gained the position of Senior Chemist in a biotechnology company. Where I utilised my undergraduate biological experience and research expertise in the synthesis of organic/macromolecule compounds to aid in the development of bioconjugates for antibody drug conjugates (ADC), anti-drug antibodies (ADA) and in-vitro diagnostics, e.g. lateral flow assay development, for a wide range of pharmaceutical and bio-pharmaceutical research.
Ghatora, Baljit K., Foot, Peter J.S., Barton, Stephen J., Thatti, Ravtej S., Papagni, Antonio and Vaghi, Luca (2017) Surface perfluoroalkyl chains segregation : a tool for reducing calcium deposits in medical grade poly(methyl methacrylate). Journal of Biomaterials and Nanobiotechnology, 8, pp. 176-187. ISSN (print) 2158-7027