Lanre Daodu

Research project: Investigation of causes, risk factors, symptoms and management of Long COVID to optimise prevention and treatment.

Abstract

Globally, Long-COVID has become a new clinical entity in the context of the SAR-CoV2 pandemic. The survivors of the acute viral infection present with a myriad of uncharacterised symptoms, which can last for several weeks to months, causing a substantial burden on the individuals. An estimated 10% -35% of individuals affected with SAR-CoV2 infection suffered persistent symptoms after recovery from the acute viral infection; this estimation could be high above 85% in those hospitalised patients with complicated COVID-19 disease.

There is no consensus on characterising the associated heterogeneous symptoms, aetiologies, risk factors and pathology underlying Long COVID syndrome. The management modalities and treatment regimens are still being debated, and the treatment is being offered symptomatically.

This study will use mixed research methods to define, characterise and stratify the symptoms, possible aetiologies and risk factors in Long-COVID individuals. Also, to determine the most effective management modalities and regimes for Long-COVID-19, develop a framework for patient stratifications based on the risk factors and possible underlying aetiologies and evidence best care guidelines for the Patients.