Dr Francesca Arrigoni

Contact

Email: f.arrigoni@kingston.ac.uk
Location: Penrhyn Road
Faculty: Faculty of Science, Engineering and Computing
School: School of Life Sciences, Pharmacy and Chemistry
Department: Department of Pharmacy

About

Dr. Francesca Arrigoni is a Senior Lecturer at Kingston in the Department of Pharmacy at Kingston (ranked #1 in London, and top 10 in the UK for Pharmacy) and has close ties working with the Infection, Immunity and Rheumatology at GOSH, the institute of Child Health, UCL which is based in the Faculty of Population Health Sciences #12 globally for Clinical, Pre-clinical & Health and in Life Sciences. Prior to that, she gained her PhD and post-doctoral experience at UCL and completed her undergraduate degree at Glasgow University with several awards and distinctions (John Hunter Medal 2 consecutive years).

Since joining Kingston University, and completing my Post-Graduate Certificate in Education I have been shortlisted for the Times Higher Education Teaching excellence award - Outstanding Research Supervisor of the year 2017 and have been awarded a Senior Fellowship of the Higher Education Academy in 2018.

I have a small research group, which as a result of a successful collaboration with UCL, aims to understand how chronic inflammation and the activation of your immune system can influence the health of your vasculature with diseases, that include HIV and also vasculitis with numerous publications in the field of endothelial and vascular physiology.

Academic responsibilities

Senior lecturer Physiology/Pharmacology

Qualifications

PhD Pharmacology UCL
BSc (Hons) Physiology Glasgow University
Senior Fellowship Higher Education Authority

Teaching and learning

Undergraduate courses taught

Postgraduate courses taught

Research

My research interests are focused upon the interaction of the vascular endothelium with various leukocyte populations under settings of vascular dysfunction and inflammatory stress.

I have developed an increasing interest in the interactions of monocytes with the vascular endothelium and have been awarded grant funding to investigate the influence of nitric oxide on monocytic motility. My current research projects investigate the role of infection in vascular disease, focussing on HIV and autoimmune and inflammatory diseases in children. These projects benefit from active and productive collaborations at the GOSH, Institute of Child Health, UCL.

I am also currently on the team for the analysis of data for the ARROW, EARNEST and CHAPAS HIV trials, carried out at GOSH, Institute of Child Health, UCL.

Publications

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Number of items: 14.

Article

Ghosh, Anshuman, Freestone, Nicholas S, Anim-Nyame, Nicholas and Arrigoni, Francesca I F (2017) Microvascular function in pre-eclampsia is influenced by insulin resistance and an imbalance of angiogenic mediators. Physiological Reports, 5(8), e13185. ISSN (online) 2051-817X

Lambden, Simon, Kelly, Peter, Ahmetaj-Shala, Blerina, Wang, Zhen, Lee, Benjamin, Nandi, Manasi, Torondel, Belen, Delahaye, Matthew, Dowsett, Laura, Piper, Sophie, Tomlinson, James, Caplin, Ben, Colman, Lucy, Boruc, Olga, Slaviero, Anna, Zhao, Lan, Oliver, Eduardo, Khadayate, Sanjay, Singer, Mervyn, Arrigoni, Francesca and Leiper, James (2015) Dimethylarginine dimethylaminohydrolase 2 regulates nitric oxide synthesis and hemodynamics and determines outcome in Polymicrobial sepsis. Arteriosclerosis, Thrombosis, and Vascular Biology, 35(6), pp. 1382-1392. ISSN (print) 1079-5642

Anim-Nyame, Nick, Ghosh, Anshuman, Freestone, Nicholas and Arrigoni, Francesca (2015) Relationship between insulin resistance and circulating endothelial cells in pre-eclampsia. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 31(10), pp. 788-791. ISSN (print) 1473-0766

Fabbri-Arrigoni, Francesca I., Clarke, Lindsey, Wang, Guosu, Charakida, Marietta, Ellins, Elizabeth, Halliday, Neil, Brogan, Paul A., Deanfield, John E., Halcox, Julian P. and Klein, Nigel (2012) Levels of circulating endothelial cells and colony forming units are influenced by age and dyslipidaemia. Pediatric Research, 72(3), pp. 299-304. ISSN (print) 0031-3998

Arrigoni, Francesca I, Matarin, Mar, Thompson, Pamela J, Michaelides, Michel, McClements, Michelle E, Redmond, Elizabeth, Clarke, Lindsey, Ellins, Elizabeth, Mohamed, Saifullah, Pavord, Ian, Hunt, David M, Moore, Anthony T, Halcox, Julian and Sisodiya, Sanjay M (2011) Extended extraocular phenotype of PROM1 mutation in kindreds with known autosomal dominant macular dystrophy. European Journal of Human Genetics, 19(2), pp. 131-137. ISSN (print) 1018-4813

Arrigoni, Francesca, Ahmetaj, Blerina and Leiper, James (2010) The biology and therapeutic potential of the DDAH/ADMA pathway. Current Pharmaceutical Design, 16(37), pp. 4089-4102. ISSN (print) 1381-6128

Clarke, LA, Hong, Y, Eleftheriou, D, Shah, V, Arrigoni, Francesca, Klein, NJ and Brogan, PA (2010) Endothelial injury and repair in systemic vasculitis of the young. Arthritis & Rheumatism, 62(6), pp. 1770-1780. ISSN (print) 0004-3591

Abdullah, A, Arrigoni, F and Freestone, N (2010) Tumour cell adhesion of endothelial cell monolayer. Journal of Pharmacy and Pharmacology, 62(10), pp. 1496-1498. ISSN (print) 0022-3573

Clarke, Lindsey, Shah, Vanita, Arrigoni, Francesca, Eleftheriou, D., Hong, Ying, Halcox, Julian, Klein, Nigel and Brogan, Paul (2008) Quantitative detection of circulating endothelial cells in vasculitis: comparison of flow cytometry and immunomagnetic bead extraction. Journal Of Thrombosis And Haemostasis, 6(6), pp. 1025-1032. ISSN (print) 1538-7933

Nandi, Manasi, Leiper, James, Arrigoni, Francesca, Hislop, Alison, Vallance, Patrick and Haywoth, Sheila (2006) Developmental regulation of GTP-CH1 in the porcine lung and its relationship to pulmonary vascular relaxation. Pediatric Research, 59(6), pp. 767-772. ISSN (print) 0031-3998

Smith, Caroline L., Birdsey, Graeme M., Anthony, Shelagh, Arrigoni, Francesca I., Leiper, James M. and Vallance, Patrick (2003) Dimethylarginine dimethylaminohydrolase activity modulates ADMA levels, VEGF expression, and cell phenotype. Biochemical and Biophysical Research Communications, 308(4), pp. 984-989. ISSN (print) 0006-291X

Arrigoni, Francesca I., Vallance, Patrick, Haworth, Sheila G. and Leiper, James M. (2003) Metabolism of asymmetric dimethylarginines is regulated in the lung developmentally and with pulmonary hypertension induced by hypobaric hypoxia. Circulation, 107(8), pp. 1195-1201. ISSN (print) 0009-7322

Achan, Vinod, Tran, Cam T.L., Arrigoni, Francesca, Whitley, Guy St.J., Leiper, James M. and Vallance, Patrick (2002) all-trans-retinoic acid increases nitric oxide synthesis by endothelial cells: a role for the induction of dimethylarginine dimethylaminohydrolase. Circulation Research, 90(7), pp. 764-769. ISSN (print) 0009-7330

Book Section

Leiper, James, Arrigoni, Francesca and Ahmetaj, Blerina (2012) The Therapeutic Potential of Dimethylarginine Dimethylaminohydrolase–Mediated Regulation of Nitric Oxide Synthesis. In: Abraham, David , Handler, Clive , Dashwood, Michael and Coghlan, Gerry, (eds.) Translational Vascular Medicine. London, U.K. : Springer Verlag. pp. (II)61-(II)88. ISBN 9780857299192

This list was generated on Sun Jan 26 05:18:10 2020 GMT.