Miss Morvarid Balouchi

Research project: Synthesis and Evaluation Quinone Nanomedicines.

Abstract

The quinone moiety is an electron-accepting functionality essential to life with key roles in aerobic respiration and photosynthesis. Small molecule quinone chemotherapeutics (e.g., mitomycin C and doxorubicin) suffer from compromised therapeutic efficacy due to poor water solubility, fast blood clearance, and adverse side effects on healthy tissues. Drug delivery with polymer nanoparticles offers therapeutic advantages, such as a large surface area for improved biocompatibility, enhanced cell permeability, drug encapsulation opportunities, and activation of therapy in response to specific physiological condition(s). This project establishes technology for the preparation of bespoke smart quinone anticancer nano-objects. The main technique used is Polymerization Induced Self-Assembly (PISA).

Biography

I received my MPharm from Kingston University in 2023 and I work as a pharmacist at East Surrey Hospital. I was awarded the Kingston University Race Equality Studentship in the same year to complete my PhD with Professor Aldabbagh. My interests are in chemistry and pharmacy practice.

Areas of research interest

  • Cancer
  • Polymer Chemistry
  • Synthesis

Qualifications

  • Pharmacy MPharm, Kingston University, University of London