I started my career as a Lecturer in the Department of Biological Sciences at the University of Calabar, Nigeria between 1980-84 after completing my PhD at North East London Polytechnic (now the University of East London). Prior to joining Kingston, I worked for more than 6 years as a Research Fellow in the Department of Histopathology at University College London and Middlesex School of Medicine. I joined Kingston University as a Senior Lecturer in Environmental Biology in 1991 and was promoted in 1997 to Principal Lecturer. I was appointed substantive Head of the School of Life Sciences in 2007, having previously been Acting Head (2004-07) and Acting Deputy Head (2002-04). I retired from the Head of School post at the end of July 2014, but returned part-time as Associate Professor in Life Sciences. I continue to teach on a number of courses and contribute to the Pathobiology and Research Methods modules. I am currently the module leader for the postgraduate Immunology and the Biology of Disease (LS7002) module. I pursue my research in collaboration with Prof Helmout Modjtahedi and Prof Andrey Karlyshev and act as second supervisor for several of their PhD students. I also currently act as the Kingston University Liaison Officer for one of our partner colleges, the College of Integrated Chinese Medicine in Reading.
Khelwatty, Said Abdullah, Essapen, Sharadah, Bagwan, Izhar, Green, Margaret, Seddon, Alan M. and Modjtahedi, Helmout (2019) Co-expression and prognostic significance of putative CSC markers CD44, CD133, wild-type EGFR and EGFRvIII in metastatic colorectal cancer. Oncotarget, 10(18), pp. 1704-1715. ISSN (online) 1949-2553
Puvanenthiran, S., Essapen, S., Haagsma, B., Bagwan, I., Green, M., Khelwatty, S. A., Seddon, A. M. and Modjtahedi, H. (2018) Co-expression and prognostic significance of the HER family members, EGFRvIII, c-MET, CD44 in patients with ovarian cancer. Oncotarget, 9, pp. 19662-19674. ISSN (online) 1949-2553
Vieira, Ana, Ramesh, Amritha, Seddon, Alan and Karlyshev, Andrey (2017) CmeABC multidrug efflux pump contributes to antibiotic resistance and promotes Campylobacter jejuni survival and multiplication in Acanthamoeba polyphaga. Applied and Environmental Microbiology, 83(22), e01600-17. ISSN (online) 1098-5336
Stanley, Aryan, Ashrafi, G. Hossein, Seddon, Alan M. and Modjtahedi, Helmout (2017) Synergistic effects of various Her inhibitors in combination with IGF-1R, C-MET and Src targeting agents in breast cancer cell lines. Scientific Reports, 7(3964), ISSN (online) 2045-2322
Lehri, B., Seddon, A. M. and Karlyshev, A. V. (2017) 'Lactobacillus fermentum' 3872 as a potential tool for combatting 'Campylobacter jejuni' infections. Virulence, 8(8), pp. 1753-1760. ISSN (print) 2150-5594
Khelwatty, Said, Essapen, Sharadah, Bagwan, Izhar, Green, Margaret, Seddon, Alan and Modjtahedi, Helmout (2016) The impact of co-expression of wild-type EGFR and its ligands determined by immunohistochemistry for response to treatment with cetuximab in patients with metastatic colorectal cancer. Oncotarget, 8(5), pp. 7666-7677. ISSN (online) 1949-2553
Puvanenthiran, Soozana, Essapen, Sharadah, Seddon, Alan and Modjtahedi, Helmout (2016) Impact of the putative cancer stem cell markers and growth factor receptor expression on the sensitivity of ovarian cancer cells to treatment with various forms of the HER inhibitors and cytotoxic drugs. International Journal Of Oncology, 49(5), pp. 1825-1838. ISSN (print) 1019-6439
Atas, Ali, Seddon, Alan M., Ford, Donna C., Cooper, Ian A., Wren, Brendan W., Oyston, Petra C. F. and Karlyshev, Andrey V. (2016) YPTB3816 of 'Yersinia pseudotuberculosis' strain IP32953 is a virulence-related metallo-oligopeptidase. BMC Microbiology, 16(282), ISSN (online) 1471-2180
Khelwatty, Said A., Essapen, Sharadah, Seddon, Alan M., Fan, Zhen and Modjtahedi, Helmout (2015) Acquired resistance to anti-EGFR mAb ICR62 in cancer cells is accompanied by an increased EGFR expression, HER-2/HER-3 signalling and sensitivity to pan HER blockers. British Journal of Cancer, 113(7), pp. 1010-1019. ISSN (print) 0007-0920
Rubinchik, Sona, Seddon, Alan and Karlyshev, Andrey (2014) A negative effect of Campylobacter capsule on bacterial interaction with an analogue of a host cell receptor. BMC Microbiology, 14(141), ISSN (online) 1471-2180
Karlyshev, Andrey, Seddon, Alan, Ramesh, Amritha, Rubinchik, Sona and Ikeda, Naomi (2017) Expression of E. coli araE and mutated lacY genes in Campylobacter jejuni is not sufficient for arabinose transport. In: Annual Applied Microbiology Conference 2017; 3 – 6 Jul 2017, Gateshead, U.K..
Lehri, Burhan, Seddon, Alan and Karlyshev, Andrey (2016) Potential use of ' Lactobacillus fermentum ' 3872 as an anti-campylobacter agent. In: The Microbiology Society Annual Conference; 21-24 Mar 2016, Liverpool, U.K..
Khelwatty, Said Abdullah, Essapen, Sharadah, Seddon, Alan M., Fan, Zhen and Modjtahedi, Helmout (2013) Acquired resistance to anti-EGFR mAb ICR62 or afatinib is accompanied by upregulation of the EGFR in colorectal cancer. In: 104th Annual Meeting of the American Association for Cancer Research; 6-10 Apr 2013, Washington, U.S.A..