Dr Stephen Wren

About

I am highly experienced in medicinal chemistry and have worked on a diverse set of biological targets over many disease areas in several organisations (Xenova, Argenta Discovery and Summit plc). I have an extensive track record in project and team management, intellectual property, drug discovery in many therapeutic areas and helped lead the chemistry effort directed towards the identification of SMTC1100 (Summit's Duchenne Muscular Dystrophy drug, currently undergoing clinical evaluation).

I have also conducted research at the Alzheimer's Research UK Oxford Drug Discovery Institute and taught at Oxford University (organic chemistry, pharmaceutical chemistry and biomedical sciences). I was a fellow of St Hilda's College, Oxford, between 2015 and 2018. I joined Kingston University London in September 2018, as a lecturer, and became a senior lecturer in 2020.

Academic responsibilities

Senior Lecturer in Organic and Pharmaceutical Chemistry

Qualifications

  • PhD (Cambridge University)
  • BSc (Hons)
  • FHEA

Teaching and learning

Research

Organic and medicinal chemistry.

Chemical and biosensors for medical and environmental applications.

Research student supervision

Publications

Number of items: 7.

Article

Scanlon, James J. and Wren, Stephen (2020) Unearthing novel thiazolidinone building blocks as carboxylic acid bioisosteres. Future Medicinal Chemistry, 12(20), pp. 1855-1864. ISSN (print) 1756-8919

Ritchie, James, Sykes, Andy, Weber, Peter and Wren, Stephen P. (2019) Immuno-oncology : the next generation of breakthrough therapies. Highlights from The Society for Medicines Research Symposium. Oxford, UK - June 21, 2019. Drugs of the Future, 44(7), pp. 599-604. ISSN (print) 0377-8282

Chanalaris, Anastasios, Doherty, Christine, Marsden, Brian D., Bambridge, Gabriel, Wren, Stephen P., Nagase, Hideaki and Troeberg, Linda (2017) Suramin inhibits osteoarthritic cartilage degradation by increasing extracellular levels of chondroprotective tissue inhibitor of metalloproteinases 3. Molecular Pharmacology, 92(4), pp. 459-468. ISSN (print) 0026-895X

Wren, Stephen P., Piletsky, Sergey A., Karim, Kal, Gascoine, Paul, Lacey, Richard, Sun, Tong and Grattan, Kenneth T. V. (2015) Computational design and fabrication of optical fibre fluorescent chemical probes for the detection of cocaine. Journal of Lightwave Technology, 33(12), pp. 2572-2579. ISSN (print) 0733-8724

Zangeneh Kamali, Khosro, Pandikumar, Alagarsamy, Sivaraman, Gandhi, Lim, Hong Ngee, Wren, Stephen Paul, Sun, Tong and Huang, Nay Ming (2015) Silver@graphene oxide nanocomposite-based optical sensor platform for biomolecules. RSC Advances, 5(23), pp. 17809-17816. ISSN (online) 2046-2069

Wren, Stephen P., Nguyen, T. Hien, Gascoine, Paul, Lacey, Richard, Sun, Tong and Grattan, Kenneth T.V. (2014) Preparation of novel optical fibre-based cocaine sensors using a molecular imprinted polymer approach. Sensors and Actuators B: Chemical, 193, pp. 35-41. ISSN (print) 0925-4005

Book Section

Wren, Stephen P. (2020) Tricyclic systems : central carbocyclic ring with fused five- and six-membered rings. In: UNSPECIFIED, (ed.) Comprehensive Heterocyclic Chemistry IV. Elsevier. ISBN 9780124095472

This list was generated on Sat Jan 23 07:11:13 2021 GMT.

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