Professor Lori Snyder
Faculties, departments and locations
- Faculty of Health, Science, Social Care and Education
- Department of Biomolecular Sciences
- School of Life Sciences, Pharmacy and Chemistry
- Penrhyn Road
Professor
- Email:
- [email protected]
About
I am involved in educating students from the foundation year to MSc programmes to PhDs. In addition, I am active in outreach activities, including Lab in a Lorry visits, offering work experience to sixth-form students, and participating in public engagement events, including making online content.
My research focuses on two main areas: combating antibiotic-resistant infections and bacterial genetics and genomics. I have developed, with my research team, novel antimicrobials to stop infant blindness from multi-drug-resistant bacterial infections. This work was featured in Wired, News Medical, and discussed on YouTube. I also use bacterial genome sequence data to uncover information about pathogens, informing our laboratory investigations. This work was featured in a YouTube interview.
In April 2020, my textbook Bacterial Genetics and Genomics was published.
I began doing genomic analyses and investigating mechanisms of antibiotic resistance during my PhD at Emory University, USA, with Prof. Bill Shafer, where I investigated Neisseria gonorrhoeae and Neisseria meningitidis. Work on these species continued during my post-doctoral research at the University of Oxford. As a post-doc at the University of Birmingham, I worked as a bioinformatician with Professors Mark Pallen and Nick Loman.
In 2013, I was awarded the W H Pierce Prize from the Society for Applied Microbiology in recognition of my substantial contributions to the science of applied microbiology. I have been twice elected to the Prokaryotic Division committee of the Microbiology Society, serve on the Editorial Boards of the journals Microorganisms (MDPI) and Microbial Genomics (Microbiology Society). Funding for my research has been awarded by Sparks, the British Society for Antimicrobial Chemotherapy, the Society for Applied Microbiology, and the Microbiology Society, as well as an NIH award on which I am a collaborator.
Qualifications
- PhD in Microbiology and Molecular Genetics, Emory University, 2001
- MA in Biology, The College of William and Mary, 1995
- BS in Biology, The College of William and Mary, 1993
- Senior Fellow HEA, 2015
Domains
My teaching is inspired by my passion for bacterial genetics and genomics, which is the focus of my textbook, Bacterial Genetics and Genomics, specifically written to motivate students to explore this exciting field. Throughout the book, I have drawn on my decades of experience as an educator to ensure that my writing is clear and supported by illustrations that don't just make the subject easy to understand, but also relatable and interesting. The topic is built from the basics through to current advances and applications. Early chapters are more than simple revision, containing information and insights important for a deep understanding of the field.
My classroom teaching has taken on several innovative approaches to engage students, including group discussions and online research in-class to innovate and brainstorm about new antimicrobial drugs. Together, we have explored the properties of existing drugs and then discussed what we would want in a new drug and how we would design it, using our smartphones and laptops in class to research what is happening now. Similarly, we have researched and shared in class exciting genome sequencing projects happening to discuss the types of sequence technologies being used, the methods of nucleic acid extractions involved, and the findings of these studies. These have developed students independent research skills, literature reading and search skills, presentation skills, critical analysis skills, and knowledge of the subjects covered in classes.
I am the module leader of our LS7020 Professional Experience module, which gives students the opportunity to gain workplace experiences relevant to their MSc degree during their studies. I developed this several years ago, and it has been praised by the IBMS during accreditation revalidation in 2018. It has also been highly praised by the students who have benefited from it. Through gaining experience in the workplace, students have told me they have found it easier to find placements and felt more confident and able to get the jobs they wanted after their graduation from Kingston University.
In 2015, I became a Senior Fellow of the Higher Education Academy (UK) based on my experience and innovations in teaching undergraduate, postgraduate, and research students, as well as mentoring and peer-supporting other academic staff. Since that time, I have engaged in Aurora training and served as an Aurora Role Model and Aurora mentor, participated in Advance HE consultancy, and assisted Advance HE in the pilot development of the external examiner training programme. I have also been part of the Kingston University Beyond Barriers staff mentoring scheme as both a mentor and mentee. Beyond Kingston, I have served as an external examiner to five institutions, four in the UK and one international, as well as examining research degrees here at Kingston University and elsewhere.
My teaching includes research-based teaching. I include students in ongoing research projects as part of their BSc and MSc projects, which has resulted in students being co-authors on peer-reviewed publications and conference abstracts.
I serve on Equality Challenge Unit panels, Kingston University institutional, and Kingston University departmental Athena Swan teams.
Qualifications
- Senior Fellow of the Higher Education Academy (2015)
- Teaching at the University level in both the classroom and the laboratory (1993 - present)
- Leadership roles in higher education and beyond (2001 - present)
- External examiner, including training by the Higher Education Academy (2013 - present)
- Bacterial Genetics and Genomics blog: https://bacterialgeneticsbiology.science.blog/
Courses taught
My research largely focuses on the pathogenic Neisseria species of bacteria: Neisseria gonorrhoeae and Neisseria meningitidis. N. gonorrhoeae causes the sexually transmitted infection gonorrhoea, as well as ophthalmia neonatorum, an infection of the eyes of newborns that can lead to blindness. N. meningitidis causes meningitis and septicaemia, life threatening conditions.
Research in my lab has been addressing the problem of antibiotic resistance in gonorrhoea infections. With the support of the Sparks charity (https://www.sparks.org.uk/) and now Antibiotic Research UK (https://www.antibioticresearch.org.uk/), we have developed a promising new alternative to antibiotics that can be used to treat ophthalmia neonatorum, featured in Wired (https://www.wired.co.uk/article/fight-against-super-gonorrhoea), News Medical (https://www.news-medical.net/news/20201009/Simple-eye-drop-can-treat-antibiotic-resistant-bacterial-infection.aspx), and detailed further here: https://www.kingston.ac.uk/news/article/2392/09-oct-2020-eye-drop-containing-natural-antimicrobial-agent-could-be-key-to-treating-antibioticresistant-bacterial-infection-that/.
Genomics research in my lab has provided novel insights into the genetic make-up of these bacterial pathogens. We are also investigating related non-pathogenic species, which provide alternative treatment options not yet explored. My genomics research led to my W H Pierce Prize from the Society for Applied Microbiology.
My genomics and antimicrobial research has resulted in numerous peer-reviewed research publications and conference presentations (listed below) selected for REF2014 and REF2021, and European patent 3354264. I am the third generation in my family to hold a patent. My father is named on a patent from his work at Yale University Hospital in respiratory therapy and his father holds a patent designed from his experiences with delivering milk for a dairy in New Haven, Connecticut.
I serve on the Editorial Board for Microbial Genomics. I have reviewed many manuscripts for over 25 quality journals in my field and been reviewer for several UKRI bodies and other national and international agencies.
I have successfully supervised seven PhD and two MSc by Research students who have graduated.
Conference listings limited to those from Kingston University.
Qualifications
- PhD in Microbiology and Molecular Genetics (2001)
- Scientific research in the fields of microbiology and genetics (1993 - present)
- https://www.researchgate.net/profile/Lori_Snyder
Specialisms
- Microbiology
- Genomics
- Bacteriology
- Genetics
- Antimicrobials
Scholarly affiliations
- https://publons.com/researcher/1180732/lori-snyder/
- https://growkudos.com/profile/lori_snyder
- Microbiology Society
- Society for Applied Microbiology
- British Society for Antimicrobial Chemotherapy
- European Society of Clinical Microbiology and Infectious Diseases
- Biochemical Society
I am an active member of the Microbiology Society, currently serving as an elected member of the Prokaryotic Division, a committee responsible for the planning and delivery of the Microbiology Society Annual Conference. I am also on the Editorial Board of the Microbiology Society journal Microbial Genomics, having previously served on the Advisory Board. Within the Society, I have also been part of the team that organised the Antimicrobial Drug Discovery from Traditional and Historical Medicine Focused Meeting in 2019 and I am leading the team organising a Focused Meeting on metagenomics in 2022. Each year, I apply to the Society to recognise one of our students for their achievements with the Undergraduate Microbiology Prize.
I am also actively involved with the Advance HE Equality Challenge Unit Athena SWAN initiative, working to address inequalities in academia. In addition to my roles within Kingston University, I regularly assess applications from other institutions as part of Athena SWAN Award assessment panels and have served as chair of such panels.
Also within AdvanceHE, I participated in the pilot programme to train external examiners and followed-up this training by participating in a trial of an online training programme for external examiners. Since that time I have regularly provided feedback to AdvanceHE on how this training has benefited me and those I have mentored. To-date, I have been external examiner for six institutions, including one university overseas. I have also been an external research degree examiner for three research degrees at three separate institutions.
As Module Leader for LS7020 Professional Experience, I have worked with outside institutions to provide opportunities for our students to develop their professional practice and knowledge. As an Aurora and Beyond Barriers mentor, I have explored with my mentees the development of their professional practice and networks.
Qualifications and expertise
- Editorial Board member of Microbial Genomics (Microbiology Society)
- Editorial Board member of Microorganisms (MDPI)
- Prokaryotic Division committee member (Microbiology Society)
- Focused Meeting organiser (Microbiology Society, 2019 & 2022)
Professional and scholarly affiliations
- Microbiology Society
- Society for Applied Microbiology
- British Society for Antimicrobial Chemotherapy
- European Society of Clinical Microbiology and Infectious Diseases
- Biochemical Society
I am the Admissions, Recruitment, and Outreach Tutor for the Department of Biomolecular Sciences and the Department of Applied and Human Sciences and a portion of the Department of Pharmaceutical Chemistry. This role is part of the AMF (Academic Management Framework) at Kingston University and involves coordination of responsibilities and scheduling for over 50 members of academic staff participating in Open Days, Experience Days, Clearing, and Outreach activities. I work together with a team of other Admissions, Recruitment, and Outreach Tutors, members of the admissions and marketing team, and admissions tutors to assess our recruitment strategies and improve applicant experiences. In this role, I have sought to improve staff work/life balance, whilst satisfying our commitment to delivering quality experiences. I have worked to enhance our Open Days, including the Department of Biomolecular Sciences and the Department of Applied and Human Sciences making use of the Outreach Centre as hub for attendees to meet staff and get answers to questions
My colleagues and I have also been successful in obtaining external funding for new outreach activities to support our public engagement programmes, both at our Outreach Centre at Kingston University and in our Lab in a Lorry. My Microbiology Society Education and Outreach funding has developed our ‘Identify. Treat.' outreach programme, centred on learning about microbes and how they are identified and treated. Working with staff and students across disciplines, I have also led in the development of a crime scene investigation outreach activity for school-age students involving forensics, geography, biology, pharmacy, and computer science.
I have been an Athena Swan Institutional Self-Assessment Team working group leader and an Athena Swan Departmental Self-Assessment Team working group leader, both with ongoing roles, duties, and responsibilities post-award. Outside of Kingston University, I have been a panel chair at the Equality Challenge Unit for the assessment of Athena Swan applications and have sat on several decision panels.
I am also an assessor for applications to the Higher Education Academy AFHEA, FHEA, and SFHEA through the KAPS programme (https://www.kingston.ac.uk/learning-and-teaching-enhancement-centre/kingston-academic-practice-standards-framework/).
External to Kingston University, I have served on the Microbiology Society Prokaryotic Division since 2015, where my leadership roles involve aspects of organisation of the Microbiology Society Annual Conference, an international conference of excellence. I was co-organiser of the Microbiology Society Focused Meeting, Antimicrobial Drug Discovery in Traditional and Historical Medicine, in 2019 and am the lead organizer of an upcoming Microbiology Society Focused Meeting on metagenomics (2022).
In 2017, I was fortunate to be supported in my leadership training by Kingston University, through the opportunity to attend the Aurora programme. I was honoured to be asked to then become an Aurora Role Model and have been pleased to have given back to this experience ever since, sharing my insight with other women across the UK and at Kingston University as an Aurora mentor.
I have also mentored women in the Beyond Barriers programme and am a mentor to an external examiner in another School within the University.
Qualifications and expertise
- Aurora, Leadership Foundation for Higher Education, 2017
- Broadcast Media Training: Control your message, ACM Training, 2019
- GDPR Essentials training, Kingston University, 2018
- Windows 10, Office 2016, Office 365 Digital Culture Training, Kingston University, 2018
- Unconscious Bias Workshop, Kingston University, 2017
- Equality Essentials, Kingston University 2017
- Athena SWAN assessment panel training, Equality Challenge Unit 2016, 2017 & 2018
- KAPS Higher Education Academy assessment panel training, Kingston University 2016, 2018
- Mentor training, Kingston University 2013, 2016, 2017 & 2018
University responsibilities
- Admissions, Recruitment, and Outreach Tutor
- Athena Swan Institutional Self-Assessment Team
- Athena Swan Departmental Self-Assessment Team
- KAPS panel assessor
- Aurora mentor
Public and Civic roles
- Equality Challenge Unit panel member (and sometimes chair)
- Microbiology Society Prokaryotic Division member
- Microbiology Society Focused Meeting organiser and co-organiser
- Aurora Role Model
Publications
Improved Neisseria gonorrhoeae culture media without atmospheric CO2
Menkiti, Chukwuma Jude and Snyder, Lori A.S., 2025, Applied Microbiology and Biotechnology (109), Published
Diversity of the type VI secretion systems in the 'Neisseria' spp
Calder, Alan and Snyder, Lori A.S., 2023, Microbial Genomics (9), 4, Published
Bacterial adaptation to venom in snakes and arachnida
Esmaeilishirazifard, Elham, Usher, Louise, Trim, Carol, Denise, Hubert, Sangal, Vartul, Tyson, Gregory H., Barlow, Axel, Redway, Keith F., Taylor, John D., Kremyda-Vlachou, Myrto, Davies, Sam, Loftus, Teresa D., Lock, Mikaella M.G., Wright, Kstir, Dalby, Andrew, Snyder, Lori A.S., Wuster, Wolfgang, Trim, Steve and Moschos, Sterghios A., 2022, Microbiology Spectrum (10), 3, Published
Challenges in treating ophthalmia neonatorum
Ukachukwu, Faith Uche, Rafiq, Afshan and Snyder, Lori A.S., 2021, Expert Review of Ophthalmology (16), 1pp 19-32, Published
The safety profile of Bald's eyesalve for the treatment of bacterial infections
Anonye, Blessing O., Nweke, Valentine, Furner-Pardoe, Jessica, Gabrilska, Rebecca, Rafiq, Afshan, Ukachukwu, Faith, Bruce, Julie, Lee, Christina, Unnikrishnan, Meera, Rumbaugh, Kendra P., Snyder, Lori A.S. and Harrison, Freya, 2020, Scientific Reports (10), Published
Virulence genes and previously unexplored gene clusters in four commensal 'Neisseria' spp. isolated from the human throat expands the neisserial gene repertoire
Calder, Alan, Menkiti, Chukwuma Jude, Çağdaş, Aylin, Santos, Jefferson Lisboa, Streich, Ricarda, Wong, Alice, Avini, Amir H., Bojang, Ebrima, Yogamanoharan, Karththeepan, Sivanesan, Nivetha, Ali, Besma, Ashrafi, Mariam, Issa, Abdirizak, Kaur, Tajinder, Latif, Aisha, Mohamed, Hani A.Sheik, Maqsood, Atifa, Tamang, Laxmi, Swager, Emily, Stringer, Alex J. and Snyder, Lori A.S., 2020, Microbial Genomics (6), 9, Published
Monocaprin eye drop formulation to combat antibiotic resistant gonococcal blindness
Churchward, Colin P., Al-Kinani, Ali A., Abdelkader, Hamdy, Swinden, Julian, Siwoku, Opeoluwa, Varnakulasingam, Thinuba, Alany, Raid G. and Snyder, Lori A.S., 2020, Scientific Reports (10), Published
The growing threat of gonococcal blindness
Dolange, Victoria, Churchward, Colin P., Christodoulides, Myron and Snyder, Lori A.S., 2018, Antibiotics (7), 3, Published
Microbial adaptation to venom is common in snakes and spiders
Denise, H., Sangal, V., Tyson, G.H., Barlow, A., Redway, K.F., Taylor, J.D., Kremyda-Vlachou, M., Loftus, T.D., Lock, M.M.G., Wright, K., Dalby, A., Snyder, L.A.S., Wuster, W., Trim, S., Moschos, S.A., Esmaeilishirazifard, E., Usher, L. and Trim, C., 2018, bioRxiv, E-pub ahead of print
Mutations in 'Neisseria gonorrhoeae' grown in sub-lethal concentrations of monocaprin do not confer resistance
Churchward, Colin P., Calder, Alan and Snyder, Lori A.S., 2018, PLoS ONE (13), 4, Published
Investigating potential chromosomal rearrangements during laboratory culture of 'Neisseria gonorrhoeae'
Spencer-Smith, Russell, Gould, Simon W., Pulijala, Madhuri and Snyder, Lori A.S., 2018, Microorganisms (6), 1, Published
Fatty acid based microemulsions to combat ophthalmia neonatorum caused by 'Neisseria gonorrhoeae' and 'Staphylococcus aureus'
Butt, Ummara, ElShaer, Amr, Snyder, Lori A.S., Al-Kinani, Ali A., Le Gresley, Adam and Alany, Raid G., 2018, Nanomaterials (8), 1, Published
Alternative antimicrobials: the properties of fatty acids and monoglycerides
Churchward, Colin P., Alany, Raid G. and Snyder, Lori A.S., 2018, Critical Reviews in Microbiology (44), 5pp 561-570, Published
Prevention of ophthalmia neonatorum caused by 'Neisseria gonorrhoea' using a fatty acid-based formulation
Churchward, Colin P., Alany, Raid G., Kirk, Ruth S., Walker, Anthony J. and Snyder, Lori A.S., 2017, mBio (8), 4, Published
Inversion of correia repeat enclosed elements in ' Neisseria gonorrhoeae '
Elbeyioglu, Firat, Roberts, Sabrina B., Spencer-Smith, Russell, Pulijala, Madhuri, Zelewska, Marta A., Nebel, Jean Christophe and Snyder, Lori A.S., 2017, Microbiology (United Kingdom) (163), 1pp 31-36, Published
Fatty acid microemulsion for the treatment of neonatal conjunctivitis: quantification, characterisation and evaluation of antimicrobial activity
Butt, Ummara, ElShaer, Amr, Snyder, Lori A.S., Chaidemenou, Athina and Alany, Raid G., 2016, Drug Delivery and Translational Research (6), 6pp 722-734, Published
Correia repeat enclosed elements and non-coding RNAs in the Neisseria species
Roberts, Sabrina B., Spencer-Smith, Russell, Shah, Mahwish, Nebel, Jean Christophe, Cook, Richard T. and Snyder, Lori A.S., 2016, Microorganisms (4), 3, Published
DNA uptake sequences in 'Neisseria gonorrhoeae' as intrinsic transcriptional terminators and markers of horizontal gene transfer
Spencer-Smith, Russell, Roberts, Sabrina, Gurung, Neesha and Snyder, Lori A.S., 2016, Microbial Genomics (2), 8, Published
Phase variable DNA repeats in 'Neisseria gonorrhoeae' influence transcription, translation, and protein sequence variation
Zelewska, Marta A., Pulijala, Madhuri, Spencer-Smith, Russell, Mahmood, Hiba Tun Noor A., Norman, Billie, Churchward, Colin P., Calder, Alan and Snyder, Lori A.S., 2016, Microbial Genomics (2016), 2, Published
Next-generation sequencing techniques
Snyder, Lori AS, 2016, Hospital Healthcare Europe (2016), Published
Finding sunken treasure in the genome sequencing data flood.
Snyder, Lori A.S., 2015, Microbiologist (16), 2pp 10-13, Published
Insight into proteomic investigations of Neisseria meningitidis serogroup C strain L91543 from analysis of its genome sequence.
Karlyshev, Andrey V., Snyder, Lori A.S., McFadden, Johnjoe and Griffin, Ruth, 2015, FEMS Microbiology Letters (362), 9, Published
Microarray analysis of the Ler regulon in enteropathogenic and enterohaemorrhagic ' Escherichia coli ' strains
Bingle, Lewis E.H., Constantinidou, Chrystala, Shaw, Robert K., Islam, Md Shahidul, Patel, Mala, Snyder, Lori A.S., Lee, David J., Penn, Charles W., Busby, Stephen J.W. and Pallen, Mark J., 2014, PLoS ONE (9), 1, Published
Epidemiological investigation of ' Pseudomonas aeruginosa ' isolates from a six-year-long hospital outbreak using high-throughput whole genome sequencing
Snyder, L. A., Loman, N. J., Faraj, L. A., Levi, K., Weinstock, G., Boswell, T. C., Pallen, M. J. and Ala'Aldeen, D. A., 2013, Eurosurveillance (18), 42, Published
Sequence features contributing to chromosomal rearrangements in 'Neisseria gonorrhoeae'
Spencer-Smith, Russell, Varkey, Eldho M., Fielder, Mark D. and Snyder, Lori A.S., 2012, PLoS ONE (7), 9, Published
Careers: a career in microbial genomics - home and away
Snyder, Lori, 2011, Microbiologist (12), 1pp 44-45, Published
Simple sequence repeats in Helicobacter canadensis and their role in phase variable expression and C-terminal sequence switching
Snyder, Lori A.S., Loman, Nicholas J., Linton, James D., Langdon, Rebecca R., Weinstock, George M., Wren, Brendan W. and Pallen, Mark J., 2010, BMC Genomics (11), 67, Published
Genome sequence of the emerging pathogen Helicobacter canadensis
Loman, N. J., Snyder, L. A.S., Linton, J. D., Langdon, R., Lawson, A. J., Weinstock, G. M., Wren, B. W. and Pallen, M. J., 2009, Journal of Bacteriology (191), 17pp 5566-5567, Published
The complete genome and proteome of Laribacter hongkongensis reveal potential mechanisms for adaptations to different temperatures and habitats
Woo, Patrick C.Y., Lau, Susanna K.P., Tse, Herman, Teng, Jade L.L., Curreem, Shirly O.T., Tsang, Alan K.L., Fan, Rachel Y.Y., Wong, Gilman K.M., Huang, Yi, Loman, Nicholas J., Snyder, Lori A.S., Cai, James J., Huang, Jian Dong, Mak, William, Pallen, Mark J., Lok, Si and Yuen, Kwok Yung, 2009, PLoS Genetics (5), 3, Published
Comparative analysis of two 'Neisseria gonorrhoeae' genome sequences reveals evidence of mobilization of Correia Repeat Enclosed Elements and their role in regulation
Snyder, Lori A.S., Cole, Jeff A. and Pallen, Mark J., 2009, BMC Genomics (10), 70, Published
Bacterial flagellar diversity and evolution: seek simplicity and distrust it?
Snyder, Lori A.S., Loman, Nicholas J., Fütterer, Klaus and Pallen, Mark J., 2009, Trends in Microbiology (17), 1pp 1-5, Published
Next-generation sequencing: the promise and perils of charting the great microbial unknown
Snyder, Lori A.S., Loman, Nick, Pallen, Mark J. and Penn, Charles W., 2009, Microbial Ecology (57), 1pp 1-3, Published
xBASE2: a comprehensive resource for comparative bacterial genomics
Chaudhuri, Roy R., Loman, Nicholas J., Snyder, Lori A.S., Bailey, Christopher M., Stekel, Dov J. and Pallen, Mark J., 2008, Nucleic Acids Research (36), Published
The repertoire of minimal mobile elements in the Neisseria species and evidence that these are involved in horizontal gene transfer in other bacteria
Snyder, Lori A.S., McGowan, Simon, Rogers, Matthew, Duro, Eris, O'Farrell, Ewan and Saunders, Nigel J., 2007, Molecular Biology and Evolution (24), 12pp 2802-2815, Published
Sequence-based analysis of pQBR103; a representative of a unique, transfer-proficient mega plasmid resident in the microbial community of sugar beet
Tett, Adrian, Spiers, Andrew J., Crossman, Lisa C., Ager, Duane, Ciric, Lena, Dow, J. Maxwell, Fry, John C., Harris, David, Lilley, Andrew, Oliver, Anna, Parkhill, Julian, Quail, Michael A., Rainey, Paul B., Saunders, Nigel J., Seeger, Kathy, Snyder, Lori A.S., Squares, Rob, Thomas, Christopher M., Turner, Sarah L., Zhang, Xue Xian, Field, Dawn and Bailey, Mark J., 2007, The ISME Journal (1), 4pp 331-340, Published
Meningococcal genetic variation mechanisms viewed through comparative analysis of Serogroup C Strain FAM18
Bentley, Stephen D., Vernikos, George S., Snyder, Lori A.S., Churcher, Carol, Arrowsmith, Claire, Chillingworth, Tracey, Cronin, Ann, Davis, Paul H., Holroyd, Nancy E., Jagels, Kay, Maddison, Mark, Moule, Sharon, Rabbinowitsch, Ester, Sharp, Sarah, Unwin, Louise, Whitehead, Sally, Quail, Michael A., Achtman, Mark, Barrell, Bart, Saunders, Nigel J. and Parkhill, Julian, 2007, PLoS Genetics (3), 2, Published
The small FNR regulon of Neisseria gonorrhoeae: comparison with the larger Escherichia coli FNR regulon and interaction with the NarQ-NarP regulon
Whitehead, Rebekah N., Overton, Tim W., Snyder, Lori A.S., McGowan, Simon J., Smith, Harry, Cole, Jeff A. and Saunders, Nigel J., 2007, BMC Genomics (8), 35, Published
Coordinated regulation of the Neisseria gonorrhoeae-truncated denitrification pathway by the nitric oxide-sensitive repressor, NsrR, and nitrite-insensitive NarQ-NarP
Overton, Tim W., Whitehead, Rebekah, Li, Ying, Snyder, Lori A.S., Saunders, Nigel J., Smith, Harry and Cole, Jeff A., 2006, Journal of Biological Chemistry (281), 44pp 33115-33126, Published
Comparison of the RpoH-dependent regulon and general stress response in Neisseria gonorrhoeae
Gunesekere, Ishara C., Kahler, Charlene M., Powell, David R., Snyder, Lori A.S., Saunders, Nigel J., Rood, Julian I. and Davies, John K., 2006, Journal of Bacteriology (188), 13pp 4769-4776, Published
The majority of genes in the pathogenic Neisseria species are present in non-pathogenic Neisseria lactamica, including those designated as 'virulence genes'
Snyder, Lori A.S. and Saunders, Nigel J., 2006, BMC Genomics (7), 128, Published
Ecf, an alternative sigma factor from Neisseria gonorrhoeae, controls expression of msrAB, which encodes methionine sulfoxide reductase
Gunesekere, Ishara C., Kahler, Charlene M., Ryan, Catherine S., Snyder, Lori A.S., Saunders, Nigel J., Rood, Julian I. and Davies, John K., 2006, Journal of Bacteriology (188), 10pp 3463-3469, Published
Complete and variant forms of the 'gonococcal genetic island' in Neisseria meningitidis
Snyder, Lori A.S., Jarvis, Stephen A. and Saunders, Nigel J., 2005, Microbiology (United Kingdom) (151), 12pp 4005-4013, Published
Comparative overview of the genomic and genetic differences between the pathogenic Neisseria strains and species
Snyder, Lori A.S., Davies, John K., Ryan, Catherine S. and Saunders, Nigel J., 2005, Plasmid (54), 3pp 191-218, Published
Genetic islands of Streptococcus agalactiae strains NEM316 and 2603VR and their presence in other Group B Streptococcal strains
Herbert, Mark A., Beveridge, Catriona J.E., McCormick, David, Aten, Emmelien, Jones, Nicola, Snyder, Lori A.S. and Saunders, Nigel J., 2005, BMC Microbiology (5), 31pp 1-11, Published
Strain-specific differences in Neisseria gonorrhoeae associated with the phase variable gene repertoire
Jordan, Philip W., Snyder, Lori A.S. and Saunders, Nigel J., 2005, BMC Microbiology (5), 21pp 1-12, Published
Microarray genomotyping of key experimental strains of Neisseria gonorrhoeae reveals gene complement diversity and five new neisserial genes associated with Minimal Mobile Elements
Snyder, Lori A.S., Davies, John K. and Saunders, Nigel J., 2004, BMC Genomics (5), 23pp 1-12, Published
Diversity in coding tandem repeats in related Neisseria spp.
Jordan, Philip, Snyder, Lori A.S. and Saunders, Nigel J., 2003, BMC Microbiology (3), 23pp 1-15, Published
A gonococcal efflux pump system enhances bacterial survival in a female mouse model of genital tract infection
Jerse, Ann E., Sharma, Nirmala D., Simms, Amy N., Crow, Emily T., Snyder, Lori A. and Shafer, William M., 2003, Infection and Immunity (71), 10pp 5576-5582, Published
Adaptation by phase variation in pathogenic bacteria
Salaün, Laurence, Snyder, Lori A.S. and Saunders, Nigel J., 2003, Advances in Applied Microbiology (52)pp 263-301, Published
Divergence and transcriptional analysis of the division cell wall (dcw) gene cluster in Neisseria spp.
Snyder, Lori A.S., Shafer, William M. and Saunders, Nigel J., 2003, Molecular Microbiology (47), 2pp 431-442, Published
The minimal mobile element
Saunders, Nigel J. and Snyder, Lori A.S., 2002, Microbiology (United Kingdom) (148), 12pp 3756-3760, Published
Comparative whole-genome analyses reveal over 100 putative phase-variable genes in the pathogenic Neisseria spp.
Snyder, L. A.S., Butcher, S. A. and Saunders, N. J., 2001, Microbiology (United Kingdom) (147), 8pp 2321-2332, Published
A putatively phase variable gene (dca) required for natural competence in Neisseria gonorrhoeae but not Neisseria meningitidis is located within the division cell wall (dcw) gene cluster
Snyder, L. A.S., Saunders, N. J. and Shafer, W. M., 2001, Journal of Bacteriology (183), 4pp 1233-1241, Published
The MtrD protein of 'Neisseria gonorrhoeae' is a member of the resistance/nodulation/division protein family constituting part of an efflux system
Hagman, Kayla E., Lucas, Claressa E., Balthazar, Jacqueline T., Snyder, Lori, Nilles, Matthew, Judd, Ralph C. and Shafer, William M., 1997, Microbiology (United Kingdom) (143), 7pp 2117-2125, Published
Bacterial genetics and genomics
Snyder, Lori A. S. (2020). Boca Raton, U.S.: [Published]
In vitro models of eye infection with Neisseria gonorrhoeae
Churchward, Colin P. and Snyder, Lori A.S. (2019). In: Christodoulides, Myron, (eds.), New York, NY: Springer Science+Business Mediapp 363-376 [Published]
Comparative genomics: the nature of CGH analysis and data interpretation
Snyder, Lori A S, Snudden, Graham, Haan, Nick and Saunders, Nigel J. (2007). In: Falciani, Francesco, (eds.), Abingdon, U.K.:pp 269-284 [Published]
Neisseria: a postgenomic view
Snyder, Lori A.S., Jordan, Philip W. and Saunders, Nigel J. (2007). In: Pullen, Mark J., Nelson, Karen E., Preston, Gail M., (eds.), Washington, U.S.A.:pp 90-119 [Published]
The neisserial genomes: what they reveal about the diversity and behavior of these species
Saunders, Nigel J. and Snyder, Lori A. S. (2005). In: Little, Peter F. R., (eds.)[Published]
Neisseria gonorrhoeae growth is inhibited by a type VI secretion system encoded within the genome of neisseria subflava strain KU1003-01
Calder, Alan and Snyder, Lori(2024). [Accepted/In press]
Neisseria subflava strain KU1003-01 outcompetes Neisseria gonorrhoeae using a contact dependant mechanism
Calder, Alan and Snyder, Lori(2023). [Accepted/In press]
Evaluation of a monoglyceride for antimicrobial activity against Gram-positive and Gram-negative bacteria
Ukachukwu, Faith, Alany, Raid and Snyder, Lori(2021). [Published]
Investigating fatty acid compounds towards developing antimicrobial therapies against infections of staphylococcal origin
Ukachukwu, Faith, Alany, Raid and Snyder, Lori(2021). [Published]
Novel antimicrobial fatty acids as potential new lines of treatment against antibiotic resistant gonococcal infections
Ukachukwu, Faith, Alany, Raid and Snyder, Lori(2021). [Published]
Exploring novel antimicrobials to treat resistant gonococcal infections
Ukachukwu, Faith, Rafiq, Afshan, Calder, Alan, Menkiti, Jude, Horsburgh, Emily, Jorge, Erik, Sookdawar, Chetna, Anwar, Sadar, Siwoku, Opeoluwa, Sriskantharajah, Vajiharan and Snyder, Lori(2020). [Published]
Fatty acids as novel treatment options for 'Pseudomonad' and 'Staphylococcal' infection
Alany, Raid, Ukachukwu, Faith and Snyder, Lori(2020). [Published]
The type VI secretion system in commensal 'Neisseria' spp.
Calder, Alan and Snyder, Lori(2020). [Published]
Antimicrobial fatty acids to combat antibiotic resistant 'Neisseria gonorrhoeae' infections.
Snyder, Lori, Ukachukwu, Faith, Jorge, Erik, Sookdawar, Chetna, Anwar, Sadaf, Siwoku, Opeoluwa, Sriskantharajah, Vajiharan, Calder, Alan, Rafiq, Afshan and Horsburgh, Emily(2020). [Accepted/In press]
The safety of a medieval remedy for the treatment of diabetic foot infections
Anonye, Blessing, Nweke, Valentine, Gabrilska, Rebecca, Rumbaugh, Kendra P, Snyder, Lori and Harrison, Freya(2020). [Accepted/In press]
Antimicrobial activity of natural oils against Neisseria gonorrhoeae, Staphylococcus aureus, and Pseudomonas aeruginosa.
Ukachukwu, Faith, Rafiq, Afshan and Snyder, Lori(2019). [Accepted/In press]
Translational and clinical considerations
Snyder, Lori(2019). [Published]
A prophylaxis and treatment for gonococcal ophthalmia neonatorum.
Snyder, Lori, Churchward, Colin, Al-Kinani, Ali, Kirk, Ruth, Walker, Anthony J., Abdelkader, Hamdy, Swindon, J, Calder, Alan, Varnakulasingam, Thinuba and Alany, Raid(2018). [Accepted/In press]
Gene clusters unique to human commensal Neisseria spp. and shared with the pathogens.
Cagdas, Aylin, Lisboa Santos, J, Ali, Besma, Ashrafi, M, Issa, A, Streich, Ricarda, Williams, D, Wong, Alice, Khakbazan, AH, Bojang, E, Yogamanoharan, K, Sivanesan, N, Snyder, Lori, Kaur, T, Latif, A, Mohamed, HAS, Maqsood, A, Tamang, L, Swager, E and Stringer, Alex(2018). [Published]
Activity of natural products against Neisseria gonorrhoeae.
Churchward, Colin, Aruda, Polliane, Sears, Andrew, Galanaki, Venetia, Arutsothy, Archana, Naidu, Puspalatha Raja, Perera, Damithi, Al-Kinani, Ali and Snyder, Lori(2018). [Accepted/In press]
Sequence variations in the human pathogen 'Neisseria gonorrhoeae' and related species
Snyder, Lori(2017). [Accepted/In press]
A promising treatment for eye infections caused by antibiotic resistant 'Neisseria gonorrhoeae'
Churchward, Colin, Alany, Raid, Kirk, Ruth, Walker, Tony and Snyder, Lori(2017). [Published]
Genome sequence analysis of four non-pathogenic Neisseria isolates reveals virulence genes.
Lisboa Santos, J, Streich, Ricarda, Wong, Alice, Khakbazan, AH, Bojang, E, Yogamanoharan, K, Sivanesan, N, Ali, Besma, Ashrafi, M, Issa, A, Kaur, T, Latif, A, Mohamed, HAS, Maqsood, A, Tamang, L, Swager, E, Snyder, Lori and Cagdas, Aylin(2017). [Published]
Identification of sequence changes in 'Neisseria gonorrhoeae' using sequencing techniques
Snyder, Lori(2016). [Accepted/In press]
DNA uptake sequences in 'Neisseria gonorrhoeae' as intrinsic transcriptional terminators and markers of horizontal gene transfer
Spencer-Smith, Russell, Roberts, Sabrina, Gurung, N and Snyder, Lori(2016). [Published]
Exploring the function of the factor H binding protein homologue in Neisseria gonorrhoeae.
Ryan, Ali, Griffin, Ruth, Snyder, Lori and Mos, Ellis(2016). [Published]
Identification of phase variable repeat changes in Neisseria gonorrhoeae using sequencing technologies.
Zelewska, Marta, Pulijala, M, Churchward, Colin, Mahmood, Hiba-Tun-Noor A and Snyder, Lori(2016). [Published]
Induced mutations in Neisseria gonorrhoeae upon repeated passage on media containing a fatty acid and a monoglyceride.
Churchward, Colin, Calder, Alan and Snyder, Lori(2016). [Published]
DNA uptake sequences in 'Neisseria gonorrhoeae' as intrinsic transcriptional terminators and markers of horizontal gene transfer
Spencer-Smith, Russell, Roberts, Sabrina, Gurung, Neesha and Snyder, Lori A. S.(2016). [Published]
Identification of phase variable repeat changes in 'Neisseria gonorrhoeae' using sequencing technologies
Zelewska, Marta, Pulijala, M, Churchward, Colin, Mahmood, Hiba-Tun-Noor A and Snyder, Lori(2016). [Published]
The diagnostic utility of circulating DNA and RNA
Snyder, Lori(2015). [Published]
Bioinformatics predictions and Ion Torrent PGM RNA-seq evidence of intrinsic transcriptional terminators in 'Neisseria gonorrhoeae'
Snyder, Lori(2015). [Published]
Identification of DNA uptake sequences in 'Neisseria gonorrhoeae' that are intrinsic transcriptional terminators using bioinformatics supported by RNA-seq
Spencer-Smith, Russell, Roberts, Sabrina, Gurung, Neesha and Snyder, Lori(2015). [Published]
Treatments of natural oils to produce bactericidal products against 'Neisseria gonorrhoeae'
Churchward, Colin, Arruda, Polliane, Sears, Andrew and Snyder, Lori(2015). [Published]
Unexpected discoveries using the Ion Torrent
Snyder, Lori(2014). [Published]
Using fatty acids to combat blindness in newborns caused by gonorrhoea infection: analytical method development and validation
Butt, U., Elshaer, A., Alany, R. and Snyder, L.(2014). [Published]
DNA uptake sequences in 'Neisseria gonorrhoeae' as intrinsic transcriptional terminators and markers of horizontal gene transfer
Spencer-Smith, R, Roberts, S, Gurung, N and Snyder, L(2014). [Published]
Genome sequence assembly, annotation, and comparative analysis of a potential novel serogroup of 'Neisseria meningitidis'
Bojang, E, Churchward, Colin, Griffin, Ruth, Roberts, Sabrina, Da Silva, RAG, Yogamanoharan, K, Sivanesan, N, Ali, B, Ashrafi, M, Issa, A, Kaur, T, Latif, A, Mohamed, HAS, Maqsood, A and Snyder, Lori(2014). [Published]
Novel antimicrobial agents against 'Neisseria gonorrhoeae' from extracts of natural products
Churchward, Colin, Sears, Andrew, Arruda, Polliane and Snyder, Lori(2014). [Published]
The Correia Enclosed Repeat Element: How it is affected by temperature, pH, CO2, and non- coding RNAs in the 'Neisseria spp.'
Roberts, Sabrina and Snyder, Lori(2014). [Published]
Meeting the challenge of "Sequencing for all"
Snyder, Lori(2014). [Accepted/In press]
Bacterial genomic changes revealed through next-generation sequencing data analysis
Snyder, Lori(2014). [Published]
Metagenomic analysis of throat swab isolates from a cohort of six Royal Holloway students
Snyder, L.A.S., Mustafa, Y., Cranenburgh, T., Smith, L. and Jansen, V.(2014). [Published]
Genome sequence assembly, annotation, and comparative analysis of a Kingston University isolate of 'Neisseria meningitidis'
Snyder, L, Yogamanoharan, K, Sivanesan, N, Ali, B, Ashrafi, M, Issa, A, Kaur, T, Latif, A, Mohamed, HAS, Maqsood, A and Bojang, E(2014). [Published]
Genomic changes in 'Neisseria gonorrhoeae' revealed through Ion Torrent sequencing
Snyder, Lori(2013). [Published]
Finding sunken treasure in the genome sequence data flood
Snyder, Lori(2013). [Published]
Discoveries in 'Neisseria gonorrhoeae' using the Ion Torrent
Snyder, Lori(2012). [Published]
Next-generation sequencing of mixed bacterial populations
Snyder, Lori(2012). [Published]
Ion PGM sequencing of mixed bacterial populations
Snyder, Lori(2012). [Published]
Comparison of RNA extraction methods for effective isolation of bacterial RNA from neisserial cultures
Roberts, S. and Snyder, L.(2012). [Published]
Comparison of the locations of Correia Repeat Enclosed Elements and potential small noncoding RNAs in the 'Neisseria' spp
Roberts, S. and Snyder, L.(2012). [Published]
Movement of Correia Repeat Enclosed Elements during laboratory culture
Elbeyioglu, F., Roberts, S., Zelewska, M., Pulijala, M., Spencer-Smith, R. and Snyder, L.(2012). [Published]
Roles for DNA repeats in 'Neisseria gonorrhoeae', including protein sequence variation
Spencer-Smith, R., Nebel, J.-C., Norman, B., Zelewska, M., Bharaj, D., Fielder, M. and Snyder, L.(2012). [Published]
Sequence features contributing to chromosomal rearrangements in 'Neisseria gonorrhoeae'
Spencer-Smith, R., Varkey, E., Fielder, M. and Snyder, L.(2012). [Published]
Next-generation sequencing of mixed bacterial populations
Snyder, Lori(2012). [Published]
Applications of Ion Torrent sequencing at Kingston University
Snyder, Lori(2012). [Published]
The Ion Torrent Personal Genome Machine in Kingston University, London
Snyder, Lori(2012). [Published]
Challenges and opportunities for smaller universities
Snyder, Lori(2011). [Published]
Use of next-generation sequencing in epidemiology
Snyder, Lori(2011). [Published]
Bacterial cell shape determining factors of Campylobacter as potential drug targets
Karlyshev, A.V., Ikeda, N. and Snyder, L.(2010). [Published]
Genome sequences and efflux systems in the pathogenic 'Neisseria'
Snyder, Lori(2010). [Published]
The changing genome of 'Neisseria gonorrhoeae'
Snyder, Lori, Smith, Russell, Aamin, Hafsa, Azam, Jibran, Bharaj, Devashish, Mtangadura, Yvonne, Shen, Rebecca and Varkey, Eldho M(2010). [Published]
The division and cell wall synthesis clusters of the commensal 'Neisseria' spp
Snyder, Lori, Marri, Pradeep Reddy, Weyand, Nathan and So, Magdalene(2010). [Published]
Next-generation sequencing of bacteria-bugs to data to discoveries
Snyder, Lori(2009). [Published]
Videos of my work
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Bacterial Genetics & Genomics About Author
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Bacterial Genetics and Genomics, not just for bacteriologists
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Combatting newborn blindness from gonorrhoea
Hear from Sparks-funded researchers Dr Lori Snyder and Professor Raid Alany as they discuss their project to help find other treatments to prevent blindness in babies as a result of gonorrhoea.
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Bacterial Genetics and Genomics Launch
Bacterial Genetics and Genomics is a new text book from Taylor & Francis' CRC Press / Garland Science, written by Dr. Lori A. S. Snyder. She highlights its features in this video, all about the launch of the book.
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Bacterial Genomics - Cholera in Haiti
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Ion PGM Sequencing of Mixed Bacterial Populations