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Research project ideas

Self-funded PhD projects

The projects listed below are interdisciplinary. Candidates are invited to discuss the project they are interested in with the proposed First Supervisor.

Aerospace and Aircraft Engineering

Civil Engineering and Construction

Computing and Information Systems

Title: Computer vision techniques, including deep learning, applied to recognition of clinical abnormalities on retinal fundus images in large datasets
First Supervisor: Dr Sarah Barman

Title: Building Full Body Illusion in Immersive Virtual Reality with Physically Based Avatars
First Supervisor: Dr Jarek Francik

Title: Human Motion Analysis using Computer Vision and Deep Learning
First Supervisor: Professor Dimitrios Makris

Title: Frame synchronization and access control in machine to machine communications
First Supervisor: Professor Maria Martini

Title: Quality assessment and modelling for Dynamic Adaptive Streaming via HTTP (DASH)
First Supervisor: Professor Maria Martini

Title: Quality assessment for light-field imaging
First SupervisorProfessor Maria Martini

Title: Big Data Modelling the Knowledge Economy
First Supervisor: Dr Robert Mellor

Title: A Bioinformatics and Machine Learning Approach to Characterise and Predict Cataract Formation
First Supervisor: Dr Jean-Christophe Nebel

Title: Game Theory for Automatic Video Annotation
First Supervisor: Dr Jean-Christophe Nebel

Title: Human Action Recognition using Machine Learning and Multimodal Data
First Supervisor: Dr Jean-Christophe Nebel

Title: Two-stream Machine Learning Architecture based on Deep Learning and HMM for Person Recognition in Images/Videos
First Supervisor: Dr Jean-Christophe Nebel

Title: Deep Learning / Bioinformatics Approach for Protein-Protein Interaction Prediction
First Supervisor: Dr Jean-Christophe Nebel

Title: Design, Implementation and Evaluation of Non-Cooperative Game Theoretic Models for Cyber Security
First Supervisor: Dr Eckhard Pfluegel

Title: 5G-IoT in the fight against Auto-immune diseases
First Supervisor: Dr Christos Politis

Title: Mid-level Summarization in First-Person-View Videos
First Supervisor: Professor Paolo Remagnino

Title: Improving Throughput in a Wireless Mobile Network using Successive Interference Cancellation with Power Randomization
First Supervisor: Dr Martin Tunnicliffe 

Title: Development of biomedical image and signal processing analysis methods
First Supervisor: Professor David Wertheim

Geography, Geology and Environment

Life Sciences

Title: Exercise and nutritional status on metabolic and hormonal responses in lean and overweight/obese individuals
First Supervisor: Dr Judith Allgrove

Title: Potential therapeutic effects of natural products in Human Papillomavirus (HPV) related cervical cancers
First Supervisor: Dr Hossein Ashrafi

Title: Role of telomere attrition in pancreatic beta cell dysfunction
First Supervisor: Dr Jess Buxton

Title: FGFR signalling in breast cancer
First Supervisor: Dr Athina-Myrto Chioni

Title: Defining the ‘molecular signature' of PARP inhibitor sensitivity in haematological malignancies
First Supervisor: Dr Terry Gaymes

Title: Investigating the modulation of cellular responses as a consequence of long term Poly ADP Ribose Polymerase (PARP) inhibition therapy
First Supervisor: Dr Terry Gaymes

Title: Investigation and Exploitation of DNA Damage and Repair in Leukaemia
First Supervisor: Dr Terry Gaymes

Title: The role of matrix interactions in regulating the SPARC family of matricellular proteins
First Supervisor: Dr Natasha Hill

Title: ß cell regeneration for diabetes therapy
First Supervisor: Dr Natasha Hill

Title: Investigation of a probiotic strain of Lactobacillus plantarum 2025 and the development of novel antibacterials
First Supervisor: Professor Andrey Karlyshev

Title: Investigating the efficacy of novel antimicrobial mixes on microorganisms, surfaces and cells lines: an integrated study
First Supervisor: Dr Alison Kelly

Title: Community pharmacists's role and training in anti-doping:  extending the SAFE YOU project
First Supervisor: Phil Crilly

Title: Multi-fidelity Optimisation of the eVTOL Wing for the Air-taxi concept
First Supervisor: Yujing Lin

Title: Biological significance, predictive value and targeting of the HER family members in pancreatic cancer
First Supervisor: Professor Helmout Modjtahedi

Title: Study of biological significance and targeting of HER family members in liver cancer
First Supervisor: Professor Helmout Modjtahedi

Title: Gender differences of ultra-endurance running: Profiling of female ultra-runners
First Supervisor: Dr Hannah Moir

Title: 'You are what you eat': Consumers, providers, and governance of human enhancement through diet
First Supervisor: Professor Declan Naughton

Title: Application of advanced analytical methods to study key aspects of health and disease
First Supervisor: Professor Declan Naughton

Title: In vitro, in vivo and ex vivo investigations of the anti-inflammatory properties of culinary herbs when combined with non-herb foods
First Supervisor: Dr Elizabeth Opara

Title: Pragmatic, positive and innovative approaches to tackle doping in amateur-, fitness- and sport to elite competitive sport
First Supervisor: Professor Andrea Petroczi

Title: Involvement of P2X7 receptors in cancer
First Supervisor: Dr Elena Polycarpou

Title: The synthesis and evaluation of chalcones, heterocyclic chalcones and related natural products as potential novel anti-microbial and anti-cancer agents
First Supervisor: Dr Sianne Schwikkard

Title: Extraction, fractionation and identification of natural products for antimicrobial analysis
First Supervisor: Dr Sianne Schwikkard

Title: Gonorrhoea antibiotic resistance, genomic changes, and evolution
First Supervisor: Dr Lori Snyder

Title: Pathogenesis of gonococcal eye infections
First Supervisor: Dr Lori Snyder

Title: Undermining the expression of gonorrhoea disease genes
First Supervisor: Dr Lori Snyder

Title: Natural products as prophylaxis and treatment for gonococcal eye infections
First Supervisor: Dr Lori Snyder

Title: The influence of a low carbohydrate high fat diet on exercise and performance
First Supervisor: Dr Owen Spendiff

Title: Molecular regulation of surface remodelling in the human pathogen Schistosoma mansoni
First Supervisor: Professor Tony Walker

Mathematics

Mechanical and Automotive Engineering

Title: Investigation of optical properties of the cornea
First Supervisor: Professor Andy Augousti

Title: Feasibility studies for novel desalination plant designs
First Supervisor: Professor Andy Augousti

Title: Fire suppression capabilities of gas-like micromist
First Supervisor: Dr Siaka Dembele

Title: Chemical Detection Using Intelligent UAV system
First Supervisor: Dr Olga Duran

Title: Mechanical Properties of Interfaces in 3D Printed Single- and Multi-Material Parts
First Supervisor: Dr Marzio Grasso

Title: Effect of Induced Plasticity on the Very High Cycle Fatigue of aluminium alloy under biaxial stress field.
First Supervisor: Dr Marzio Grasso

Title: Enhancement of electrical conductivity of carbon fibre composite for resisting lightening strike on aircrafts
First Supervisor: Dr Homayoun Hadavinia

Title: Additive manufacturing of metal components using FDM technology
First Supervisor: Dr Hany Hassanin

Title: Graphene/ceramic nanocomposites for fireproof applications
First Supervisor: Dr Hany Hassanin

Title: Numerical simulation of Deflagration, Detonation and DDT in large scale inhomogeneous reactive mixtures
First Supervisor: Dr Ali Heidari

Title: Computational modelling and simulation of bio-inspired structures
First Supervisor: Dr Payam Khazaeinejad

Title: Shape optimisation for aesthetics/functional requirements in the context of additive manufacturing
First Supervisor: Dr Payam Khazaeinejad

Title: Hybrid-type finite elements for thermomechanical problems
First Supervisor: Dr Payam Khazaeinejad

Title: An investigation into transonic flows over high pressure gas turbine blade tip
First Supervisor: Dr Zinab Saleh

Title: Combustion and detonation of hydrogen with suspended particles and droplets
First Supervisor: Dr Konstantin Volkov

Title: Design and optimisation of wind farms built-in to existing buildings and civil objects
First Supervisor: Dr Konstantin Volkov

Title: Particulate systems in fire safety engineering
First Supervisor: Dr Konstantin Volkov

Title: Tap water treatment with a laser pulse
First Supervisor: Dr Konstantin Volkov

Title: Knowledge based process planning using manufacturing big data
First Supervisor: Dr Xianzhi Zhang

Title: Resilient and Lightweight Unmanned Aerial Vehicle for Extreme Environment
First Supervisor: Dr Yahya Zweiri

Pharmacy and Chemistry

Title: Lead isotope ratio measurements in microcosms and avian samples as indicators for the source of lead poisoning in wildfowl
First Supervisor: Dr James Barker

Title: Synthesis and Properties of Novel thermoresponsive polymers for water purification
First Supervisor: Dr Stephen Barton

Title: Modification of antibiotics to improve efficacy / safety
First Supervisor: Dr Ian Beadham

Title: Exploring "inverse vulcanisation" sulphur polymers and their analogues for 3D printing, healthcare and catalysis
First Supervisor: Dr Joseph C Bear

Title: Development of low molecular weight organogelators
First Supervisor: Dr Joseph C Bear

Title: Characterisation of the role of Panx1/Panx2 in primary endothelial cells 
First Supervisor: Dr Miyyada Boumechache

Title: Development of Smart Nanocapsules for Targeted Anti-Cancer Drug Delivery
First Supervisor: Dr Gianpiero Calabrese

Title: Carbon nanotubes in the boron neutron capture therapy of cancer
First Supervisor: Dr Gianpiero Calabrese

Title: Development and evaluation of games and computer simulations to teach physiology
First Supervisor: Dr Mark Carew

Title: Study of the osmopressor response in human volunteers with and without hypertension
First Supervisor: Dr Mark Carew

Title: Community pharmacists' role and training in anti-doping: Extending the SAFE YOU project
First Supervisor: Philip Crilly

Title: Medicated dental implants
First Supervisor: Dr Amr ElShaer

Title: New generation of orally disintegrating tablets: modified and sustained release
First Supervisor: Dr Amr ElShaer

Title: Chitosan-electroactive polymer blends and grafted copolymers as potential smart drug-delivery materials
First Supervisor: Dr John Fletcher

Title: Ileo-colonic targeted drug delivery
First Supervisor: Dr John Fletcher

Title: Investigating patterning genes in CNS regeneration in planaria
First Supervisor: Dr Francesca Mackenzie

Title: Investigating neuronal patterning and development
First Supervisor: Dr Francesca Mackenzie

Title: Investigating metabolic changes in neurodegeneration
First Supervisor: Dr Francesca Mackenzie

Title: Magnetic-polymer hydrogels for controlled drug release
First Supervisor: Dr Ayomi Perera

Title: Novel assays for screening drug – lipid membrane interactions
First Supervisor: Dr Gemma Shearman

Title: Oral delivery of insulin for diabetes therapy: Development and evaluation of insulin loaded polymer/lipid based carrier systems
First Supervisor: Dr Anil Vangala

Title: Synthesis of biologically active molecules
First Supervisor: Dr Stephen Wren

Title: Synthesis of a toolbox of bioisosteric building blocks for drug discovery
First Supervisor: Dr Stephen Wren

Faculty of Science, Engineering and Computing
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